CAS 67439-82-1|PEG3

Introduction:Basic information about CAS 67439-82-1|PEG3, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NamePEG3
CAS Number67439-82-1Molecular Weight164.20000
Density1.091 g/mL at 20ºCBoiling Point283.02ºC at 760 mmHg
Molecular FormulaC7H16O4Melting Point/
MSDSChineseUSAFlash Point124.966ºC
Symbol
GHS05
Signal WordDanger

Names

Name2-[3-(2-hydroxyethoxy)propoxy]ethanol
SynonymMore Synonyms

PEG3 BiologicalActivity

DescriptionPEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related CatalogResearch Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density1.091 g/mL at 20ºC
Boiling Point283.02ºC at 760 mmHg
Molecular FormulaC7H16O4
Molecular Weight164.20000
Flash Point124.966ºC
Exact Mass164.10500
PSA58.92000
Index of Refractionn20/D 1.456
InChIKeyKXSKAZFMTGADIV-UHFFFAOYSA-N
SMILESOCCOCCCOCCO

Safety Information

Symbol
GHS05
Signal WordDanger
Hazard StatementsH318
Precautionary StatementsP280-P305 + P351 + P338
Personal Protective EquipmentEyeshields;Gloves
Hazard CodesC
RIDADRNONH for all modes of transport

Synonyms

2-[3-(2-hydroxyethoxy)propoxy]ethan-1-ol
1,3-Bis-(2-hydroxy-aethoxy)-propan
2,2'-propane-1,3-diyldioxy-bis-ethanol
2,2'-(Trimethylenedioxy)diethanol
Ethanol,2,2'-[1,3-propanediylbis(oxy)]bis
3,7-Dioxa-1,9-nonanediol
1,9-Dihydroxy-3,7-dioxanonane
3,7-dioxa-nonane-1,9-diol
1,3-bis-(2-hydroxy-ethoxy)-propane
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