CAS 55928-65-9|(Z)-dodec-2-enoic acid
| Common Name | (Z)-dodec-2-enoic acid | ||
|---|---|---|---|
| CAS Number | 55928-65-9 | Molecular Weight | 198.30 |
| Density | 0.922 g/cm3 | Boiling Point | 311.7ºC at 760 mmHg |
| Molecular Formula | C12H22O2 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 216.6ºC |
| Symbol | GHS05, GHS09 | Signal Word | Danger |
Names
| Name | cis-2-Dodecenoic acid |
|---|---|
| Synonym | More Synonyms |
(Z)-dodec-2-enoic acid BiologicalActivity
| Description | cis-2-Dodecenoic acid, originally discovered in Burkholderia cenocepacia, can interfere with the bacterial quorum sensing system and inhibit bacterial biofilm formation and virulence factor production[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Yinyue Deng, et al. Cis-2-dodecenoic acid signal modulates virulence of Pseudomonas aeruginosa through interference with quorum sensing systems and T3SS. BMC Microbiol. 2013 Oct 18;13:231. |
Chemical & Physical Properties
| Density | 0.922 g/cm3 |
|---|---|
| Boiling Point | 311.7ºC at 760 mmHg |
| Molecular Formula | C12H22O2 |
| Molecular Weight | 198.30 |
| Flash Point | 216.6ºC |
| Exact Mass | 198.16200 |
| PSA | 37.30000 |
| LogP | 3.76790 |
| InChIKey | PAWGRNGPMLVJQH-KHPPLWFESA-N |
| SMILES | CCCCCCCCCC=CC(=O)O |
| Storage condition | -20°C |
Safety Information
| Symbol | GHS05, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H318-H411 |
| Precautionary Statements | P273-P280-P305 + P351 + P338 |
| Hazard Codes | Xi |
| RIDADR | UN 3077 9 / PGIII |
Articles3
More Articles| Intraspecies signaling involving the diffusible signal factor BDSF (cis-2-dodecenoic acid) influences virulence in Burkholderia cenocepacia. J. Bacteriol. 191(15) , 5013-5019, (2009) Burkholderia cenocepacia produces a diffusible fatty acid signal molecule, cis-2-dodecenoic acid (BDSF), that has been implicated in interspecies and interkingdom communication. Here, we show that BDS... | |
| The AHL- and BDSF-dependent quorum sensing systems control specific and overlapping sets of genes in Burkholderia cenocepacia H111. PLoS ONE 7 , e49966, (2012) Quorum sensing in Burkholderia cenocepacia H111 involves two signalling systems that depend on different signal molecules, namely N-acyl homoserine lactones (AHLs) and the diffusible signal factor cis... | |
| Cis-2-dodecenoic acid quorum sensing system modulates N-acyl homoserine lactone production through RpfR and cyclic di-GMP turnover in Burkholderia cenocepacia. BMC Microbiol. 13 , 148, (2013) Burkholderia cenocepacia employs both N-Acyl homoserine lactone (AHL) and cis-2-dodecenoic acid (BDSF) quorum sensing (QS) systems in regulation of bacterial virulence. It was shown recently that disr... |
Synonyms
| (2Z)-2-Dodecenoic acid |
