CAS 120205-50-7|(2R,3R)-BOC-dolaproine

Introduction：Basic information about CAS 120205-50-7|(2R,3R)-BOC-dolaproine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. (2R,3R)-BOC-dolaproine BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	(2R,3R)-BOC-dolaproine
CAS Number	120205-50-7	Molecular Weight	287.352
Density	1.1±0.1 g/cm3	Boiling Point	397.8±17.0 °C at 760 mmHg
Molecular Formula	C₁₄H₂₅NO₅	Melting Point	/
MSDS	/	Flash Point	194.4±20.9 °C

Names

Name	(2R,3R)-3-((S)-1-(tert-Butoxycarbonyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoic acid
Synonym	More Synonyms

(2R,3R)-BOC-dolaproine BiologicalActivity

Description	N-Boc-dolaproine (Dap) is the amino acid residue of the pentapeptide Dolastatin 10 (HY-15580). Dolastatin 10 inhibits tubulin polymerization and mitosis and has anticancer activity[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>Others >>Others
References	[1]. Almeida W P, et al. An easy and stereoselective synthesis of N-Boc-dolaproine via the Baylis–Hillman reaction[J]. Tetrahedron letters, 2003, 44(5): 937-940.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	397.8±17.0 °C at 760 mmHg
Molecular Formula	C₁₄H₂₅NO₅
Molecular Weight	287.352
Flash Point	194.4±20.9 °C
Exact Mass	287.173279
PSA	76.07000
LogP	1.36
Vapour Pressure	0.0±2.0 mmHg at 25°C
Index of Refraction	1.490
InChIKey	LNEHHTWYEBGHBY-OUAUKWLOSA-N
SMILES	COC(C(C)C(=O)O)C1CCCN1C(=O)OC(C)(C)C

Synonyms

(2R,3R)-3-Methoxy-2-methyl-3-[(2S)-1-{[(2-methyl-2-propanyl)oxy]carbonyl}-2-pyrrolidinyl]propanoic acid

2-Pyrrolidinepropanoic acid, 1-[(1,1-dimethylethoxy)carbonyl]-β-methoxy-α-methyl-, (αR,βR,2S)-

(2R,3R)-3-methoxy-2-methyl-3-[(2S)-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidin-2-yl]propanoic acid

((2R,3R)-3-((S)-1-(tertbutoxycarbonyl)pyrrolidin-2-yl)-3-Methoxy-2-Methylpropanoic acid

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