CAS 152305-87-8|sulfo-NHS-acetate

Introduction：Basic information about CAS 152305-87-8|sulfo-NHS-acetate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. sulfo-NHS-acetate BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Customs
6. Synonyms

Common Name	sulfo-NHS-acetate
CAS Number	152305-87-8	Molecular Weight	237.18700
Density	1.8g/cm3	Boiling Point	/
Molecular Formula	C₆H₇NO₇S	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	1-acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid
Synonym	More Synonyms

sulfo-NHS-acetate BiologicalActivity

Description	Sulfo-NHS-Acetate is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker
Target	Alkyl-Chain
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Chemical & Physical Properties

Density	1.8g/cm3
Molecular Formula	C₆H₇NO₇S
Molecular Weight	237.18700
Exact Mass	236.99400
PSA	126.43000
Index of Refraction	1.583
InChIKey	MDUQWFYJHRLNRN-UHFFFAOYSA-N
SMILES	CC(=O)ON1C(=O)CC(S(=O)(=O)O)C1=O

Safety Information

Hazard Codes	Xi
HS Code	2925190090

Customs

HS Code	2925190090
Summary	2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Synonyms

Sulfo-nhs-acetate

BIM103

Sulfosuccinimidyl acetate

3-Pyrrolidinesulfonicacid,1-(acetyloxy)-2,5-dioxo

1-Acetoxy-2,5-dioxopyrrolidine-3-sulfonic acid

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