CAS 73554-84-4|Boc-Val-Leu-Lys-AMC acetate salt

Introduction:Basic information about CAS 73554-84-4|Boc-Val-Leu-Lys-AMC acetate salt, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameBoc-Val-Leu-Lys-AMC acetate salt
CAS Number73554-84-4Molecular Weight615.76100
Density1.166g/cm3Boiling Point866.8ºC at 760 mmHg
Molecular FormulaC32H49N5O7Melting Point/
MSDS/Flash Point478ºC

Names

Nameboc-val-leu-lys-amc acetate
SynonymMore Synonyms

Boc-Val-Leu-Lys-AMC acetate salt BiologicalActivity

DescriptionBoc-Val-Leu-Lys-AMC is a sensitive, fluorogenic, and specific substrate of plasmin, as well as acrosin from the ascidian Halocynthia roretzi, porcine calpain isozymes I and II, and papain[1][2][3][4].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
Target

others

References

[1]. T Sasaki, et al. Comparative specificity and kinetic studies on porcine calpain I and calpain II with naturally occurring peptides and synthetic fluorogenic substrates. J Biol Chem. 1984 Oct 25;259(20):12489-94.  

[2]. R E Smith, et al. Direct photometric or fluorometric assay of proteinases using substrates containing 7-amino-4-trifluoromethylcoumarin. Thromb Res. 1980 Feb;17(3-4):393-402.  

[3]. H Kato, et al. New fluorogenic peptide substrates for plasmin. J Biochem. 1980 Jul;88(1):183-90.  

Chemical & Physical Properties

Density1.166g/cm3
Boiling Point866.8ºC at 760 mmHg
Molecular FormulaC32H49N5O7
Molecular Weight615.76100
Flash Point478ºC
Exact Mass615.36300
PSA181.86000
LogP5.67990
Index of Refraction1.546
InChIKeyKVLPXRKIIFWZLM-DPZBCOQUSA-N
SMILESCc1cc(=O)oc2cc(NC(=O)C(CCCCN)NC(=O)C(CC(C)C)NC(=O)C(NC(=O)OC(C)(C)C)C(C)C)ccc12
Storage condition−20°C

Safety Information

WGK Germany3

Synonyms

Boc-VLK-MCA
BOC-VAL-LEU-LYS-AMC ACOH
MFCD00038453
N-T-BOC-VAL-LEU-LYS 7-AMIDO-4-METHYLCOUMARIN
Boc-Val-Leu-Lys-AMC
N-tert-BOC-Val-Leu-Lys 7-amido-4-methylcoumarin
BOC-VAL-LEU-LYS-7-AMIDO-4-METHYLCOUMARIN
EINECS 277-536-9
BOC-VAL-LEU-LYS-MCA
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