Introduction:Basic information about CAS 14317-68-1|[Asu1,6]-Oxytocin, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | [Asu1,6]-Oxytocin |
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| CAS Number | 14317-68-1 | Molecular Weight | 956.09600 |
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| Density | 1.216g/cm3 | Boiling Point | 1475.3ºC at 760 mmHg |
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| Molecular Formula | C45H69N11O12 | Melting Point | / |
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| MSDS | / | Flash Point | 846ºC |
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Names
| Name | deamino-dicarba-oxytocin |
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| Synonym | More Synonyms |
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[Asu1,6]-Oxytocin BiologicalActivity
| Description | [Asu1,6]-Oxytocin is an analog of oxytocin. [Asu1,6]-Oxytocin reverses insulin resistance and glucose intolerance prior to reduction of obesity. [Asu1,6]-Oxytocin has the potential for the research of obesity and diabetes[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Metabolic Disease |
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| In Vivo | [Asu1,6]-Oxytocin (4 μg per injection; third-ventricle injection, twice injected for 7 days) 改善小鼠的葡萄糖耐受不良并降低空腹血胰岛素水平[1]。 Animal Model: C57BL/6 mice[1] Dosage: 4 μg per injection Administration: Third-ventricle injection, twice injected for 7 days Result: Improved glucose intolerance and lowered fasting blood insulin levels, and both effects were independent of body weight. |
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| References | [1]. Zhang H, et al. Treatment of obesity and diabetes using oxytocin or analogs in patients and mouse models. PLoS One. 2013 May 20;8(5):e61477. |
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Chemical & Physical Properties
| Density | 1.216g/cm3 |
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| Boiling Point | 1475.3ºC at 760 mmHg |
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| Molecular Formula | C45H69N11O12 |
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| Molecular Weight | 956.09600 |
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| Flash Point | 846ºC |
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| Exact Mass | 955.51300 |
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| PSA | 373.51000 |
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| LogP | 2.09780 |
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| Vapour Pressure | 0mmHg at 25°C |
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| Index of Refraction | 1.531 |
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| InChIKey | BNUVXRORJOWJBK-DTRKZRJBSA-N |
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| SMILES | CCC(C)C1NC(=O)C(Cc2ccc(O)cc2)NC(=O)CCCCCC(C(=O)N2CCCC2C(=O)NC(CC(C)C)C(=O)NCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(CCC(N)=O)NC1=O |
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Synonyms
| tyr-ile-gln-asn-asu-pro-leu-gly-nh2 |