CAS 20329-96-8|Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate

Introduction:Basic information about CAS 20329-96-8|Methyl trans-3-(3,4,5-trimethoxyphenyl)acrylate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameMethyl trans-3-(3,4,5-trimethoxyphenyl)acrylate
CAS Number20329-96-8Molecular Weight252.263
Density1.1±0.1 g/cm3Boiling Point370.6±37.0 °C at 760 mmHg
Molecular FormulaC13H16O5Melting Point91-92ºC
MSDS/Flash Point163.5±26.5 °C

Names

Namemethyl 3,4,5-trimethoxycinnamate
SynonymMore Synonyms

BiologicalActivity

Description(E)-Methyl 3,4,5-trimethoxycinnamate is a bioactive natural phenylpropanoid. (E)-Methyl 3,4,5-trimethoxycinnamate suppresses inflammation in RAW264.7 macrophages and blocks macrophage-adipocyte interaction. (E)-Methyl 3,4,5-trimethoxycinnamate also has antiarrhythmic effect, leads to suppression of triggered activities in rabbit myocytes[1][2].
Related CatalogSignaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology
References

[1]. Olajide OA, et al. Methyl 3,4,5-trimethoxycinnamate suppresses inflammation in RAW264.7 macrophages and blocks macrophage-adipocyte interaction. Inflammopharmacology. 2020 Oct;28(5):1315-1326.  

[2]. Zhao Z, et al. Potential antiarrhythmic effect of methyl 3,4,5-trimethoxycinnamate, a bioactive substance from roots of polygalae radix: suppression of triggered activities in rabbit myocytes. Biol Pharm Bull. 2013;36(2):238-44.  

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point370.6±37.0 °C at 760 mmHg
Melting Point91-92ºC
Molecular FormulaC13H16O5
Molecular Weight252.263
Flash Point163.5±26.5 °C
Exact Mass252.099777
PSA53.99000
LogP1.77
Vapour Pressure0.0±0.8 mmHg at 25°C
Index of Refraction1.529
InChIKeyKLXHCGFNNUQTEY-AATRIKPKSA-N
SMILESCOC(=O)C=Cc1cc(OC)c(OC)c(OC)c1

Safety Information

HS Code2918990090

Customs

HS Code2918990090
Summary2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Synonyms

2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-, methyl ester
Methyl (2E)-3-(3,4,5-trimethoxyphenyl)acrylate
methyl (2E)-3-(3,4,5-trimethoxyphenyl)prop-2-enoate
Methyl 3,4,5-trimethoxycinnamate
2-Propenoic acid, 3-(3,4,5-trimethoxyphenyl)-, methyl ester, (2E)-
Methyl trans-3,4,5-trimethoxycinnamate
Methyl (E)-6,7,8-trimethoxycinnamate
3,4,5-trimethoxycinnamic acid methyl ester
Methyl 3,4,5-TriMethyl cinnaMate
Cinnamic acid, 3,4,5-trimethoxy-, methyl ester
Methyl 3,4,5-trimethoxy-trans-cinnamate
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