Introduction：Basic information about CAS 55489-58-2|2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | 2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol |
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| CAS Number | 55489-58-2 | Molecular Weight | 240.296 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 358.0±27.0 °C at 760 mmHg |
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| Molecular Formula | C13H20O4 | Melting Point | / |
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| MSDS | / | Flash Point | 170.3±23.7 °C |
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Names
| Name | Triethylene Glycol Monobenzyl Ether |
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| Synonym | More Synonyms |
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2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol BiologicalActivity
| Description | Triethylene glycol monobenzyl ether is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>PROTAC >>PROTAC Linker |
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| Target | PEGs |
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| In Vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
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| References | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 358.0±27.0 °C at 760 mmHg |
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| Molecular Formula | C13H20O4 |
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| Molecular Weight | 240.296 |
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| Flash Point | 170.3±23.7 °C |
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| Exact Mass | 240.136154 |
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| PSA | 47.92000 |
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| LogP | 0.54 |
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| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
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| Index of Refraction | 1.506 |
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| InChIKey | KVPHZILZNXDCNH-UHFFFAOYSA-N |
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| SMILES | OCCOCCOCCOCc1ccccc1 |
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Safety Information
| Hazard Codes | Xi |
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| HS Code | 2909499000 |
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Customs
| HS Code | 2909499000 |
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| Summary | 2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0% |
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Synonyms
| 2-[2-(2-phenylmethoxyethoxy)ethoxy]ethanol |
| Ethanol, 2-[2-[2-(phenylmethoxy)ethoxy]ethoxy]- |
| MFCD02093556 |
| 2-{2-[2-(Benzyloxy)ethoxy]ethoxy}ethanol |
