CAS 575-04-2|7-Methoxy-4-(trifluoromethyl)coumarin
| Common Name | 7-Methoxy-4-(trifluoromethyl)coumarin | ||
|---|---|---|---|
| CAS Number | 575-04-2 | Molecular Weight | 244.16700 |
| Density | 1.418g/cm3 | Boiling Point | 287.4ºC at 760 mmHg |
| Molecular Formula | C11H7F3O3 | Melting Point | / |
| MSDS | ChineseUSA | Flash Point | 123.6ºC |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | 7-Methoxy-4-(trifluoromethyl)coumarin |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.418g/cm3 |
|---|---|
| Boiling Point | 287.4ºC at 760 mmHg |
| Molecular Formula | C11H7F3O3 |
| Molecular Weight | 244.16700 |
| Flash Point | 123.6ºC |
| Exact Mass | 244.03500 |
| PSA | 39.44000 |
| LogP | 2.82040 |
| Index of Refraction | 1.506 |
| InChIKey | HAZHUELNIGDYQH-UHFFFAOYSA-N |
| SMILES | COc1ccc2c(C(F)(F)F)cc(=O)oc2c1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S36 |
| RIDADR | NONH for all modes of transport |
| HS Code | 2932209090 |
Customs
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles5
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| Physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hydroxypyridin-4-one hybrid molecules with antimalarial activity. Expert Opin. Drug Metab. Toxicol. 10(10) , 1313-24, (2014) Drug resistance by Plasmodium falciparum remains a challenge in malaria chemotherapy. This paper will focus on physicochemical and drug metabolism characterization of a series of 4-aminoquinoline-3-hy... | |
| Effects of artemisinin antimalarials on Cytochrome P450 enzymes in vitro using recombinant enzymes and human liver microsomes: potential implications for combination therapies. Xenobiotica 44(7) , 615-26, (2014) 1. Cytochrome P450 enzyme system is the most important contributor to oxidative metabolism of drugs. Modification, and more specifically inhibition, of this system is an important determinant of sever... |
Synonyms
| 7-methoxy-4-(trifluoromethyl)chromen-2-one |
