CAS 2013-58-3|GS-2989

[1]. Fuoco D. Cytotoxicity induced by tetracyclines via protein photooxidation[J]. Advances in Toxicology, et al. Cytotoxicity induced by tetracyclines via protein photooxidation[J]. Advances in Toxicology, 2015, 2015.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

QI7830000

CHEMICAL NAME :

2-Naphthacenecarboxamide, 7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octah ydro- 3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-

CAS REGISTRY NUMBER :

2013-58-3

LAST UPDATED :

198803

DATA ITEMS CITED :

3

MOLECULAR FORMULA :

C22-H21-Cl-N2-O8

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

2 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,1022,1972

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

5 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 22,1022,1972

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

425 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

GICTAL Giornale Italiano di Chemioterapia. Italian Journal of Chemotherapy. (Edizioni Minerva Medica, Casella Postale 491, I-10126 Turin, Italy) V.1- 1954- Volume(issue)/page/year: 17,276,1970