CAS 3881-21-8|2'-(o-methyl)-inosine

Introduction:Basic information about CAS 3881-21-8|2'-(o-methyl)-inosine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name2'-(o-methyl)-inosine
CAS Number3881-21-8Molecular Weight282.25
Density1.844g/cm3Boiling Point669.568ºC at 760 mmHg
Molecular FormulaC11H14N4O5Melting Point/
MSDS/Flash Point358.742ºC

Names

Name9-[(2R,3R,4R,5R)-4-hydroxy-5-(hydroxymethyl)-3-methoxyoxolan-2-yl]-3H-purin-6-one
SynonymMore Synonyms

2'-(o-methyl)-inosine BiologicalActivity

Description9-((2R,3R,4R,5R)-4-Hydroxy-5-(hydroxymethyl)-3-methoxytetrahydrofuran-2-yl)-9H-purin-6-ol (2'-O-methylinosine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related CatalogSignaling Pathways >>Cell Cycle/DNA Damage >>Nucleoside Antimetabolite/AnalogResearch Areas >>Others
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

Density1.844g/cm3
Boiling Point669.568ºC at 760 mmHg
Molecular FormulaC11H14N4O5
Molecular Weight282.25
Flash Point358.742ºC
Exact Mass282.09600
PSA122.49000
Appearance of CharactersPowder | White to Off-white
Index of Refraction1.774
Water SolubilitySlightly soluble in water.

Synonyms

2'-O-methylinosine
O2'-methyl-inosine
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