Introduction：Basic information about CAS 83-30-7|Phloroglucinol carboxylic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Phloroglucinol carboxylic acid |
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| CAS Number | 83-30-7 | Molecular Weight | 170.120 |
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| Density | 1.7±0.1 g/cm3 | Boiling Point | 426.5±30.0 °C at 760 mmHg |
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| Molecular Formula | C7H6O5 | Melting Point | ~210 °C (dec.) |
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| MSDS | / | Flash Point | 225.9±21.1 °C |
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Names
| Name | 2,4,6-Trihydroxybenzoic Acid |
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| Synonym | More Synonyms |
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Phloroglucinol carboxylic acid BiologicalActivity
| Description | 2,4,6-Trihydroxybenzoic acid, the flavonoid metabolite, is a CDK inhibitor. 2,4,6-Trihydroxybenzoic acid can be used for the research of cancer[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Cell Cycle/DNA Damage >>CDK |
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| References | [1]. Sankaranarayanan R, et, al. The Flavonoid Metabolite 2,4,6-Trihydroxybenzoic Acid Is a CDK Inhibitor and an Anti-Proliferative Agent: A Potential Role in Cancer Prevention. Cancers (Basel). 2019 Mar 26;11(3):427. |
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Chemical & Physical Properties
| Density | 1.7±0.1 g/cm3 |
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| Boiling Point | 426.5±30.0 °C at 760 mmHg |
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| Melting Point | ~210 °C (dec.) |
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| Molecular Formula | C7H6O5 |
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| Molecular Weight | 170.120 |
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| Flash Point | 225.9±21.1 °C |
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| Exact Mass | 170.021530 |
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| PSA | 97.99000 |
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| LogP | 1.80 |
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| Vapour Pressure | 0.0±1.1 mmHg at 25°C |
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| Index of Refraction | 1.730 |
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| InChIKey | IBHWREHFNDMRPR-UHFFFAOYSA-N |
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| SMILES | O=C(O)c1c(O)cc(O)cc1O |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- DH8910000
- CHEMICAL NAME :
- Benzoic acid, 2,4,6-trihydroxy-
- CAS REGISTRY NUMBER :
- 83-30-7
- BEILSTEIN REFERENCE NO. :
- 2212148
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C7-H6-O5
- MOLECULAR WEIGHT :
- 170.13
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 196,478,1976
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S22-S24/25-S26-S37/39 |
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| WGK Germany | 3 |
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| RTECS | DH8910000 |
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| HS Code | 2918290000 |
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Customs
| HS Code | 2918290000 |
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| Summary | HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0% |
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Synonyms
| Phloroglucinic acid |
| Phloroglucinol carboxylic acid |
| Phloroglucinolcarboxylic acid |
| 2,4,6-Trihydroxybenzoic acid |
| Benzoic acid, 2,4,6-trihydroxy- |
| EINECS 201-467-5 |
| MFCD00002453 |
