CAS 84601-19-4|Oleyloxyethyl Phosphorylcholine

Introduction：Basic information about CAS 84601-19-4|Oleyloxyethyl Phosphorylcholine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameOleyloxyethyl Phosphorylcholine
CAS Number84601-19-4Molecular Weight477.66
Density/Boiling Point/
Molecular FormulaC25H52NO5PMelting Point/
MSDS/Flash Point/

Names

Nameoleyloxyethyl phosphorylcholine
SynonymMore Synonyms

Oleyloxyethyl Phosphorylcholine BiologicalActivity

Description(Z)-Oleyloxyethyl phosphorylcholine ((Z)-OPC) is an isomer of Oleyloxyethyl phosphorylcholine (OPC). Oleyloxyethyl phosphorylcholine is an inhibitor of secreted Phospholipase A2 (sPLA2), which is involved in the biosynthesis of proinflammatory lipid media. Oleyloxyethyl phosphorylcholine can be used to study inflammatory diseases. Oleyloxyethyl phosphorylcholine also modified the red blood membrane and was used to bind the oxygen-carrying liquid perfluorocarbons as an antivenom agent to reduce toxin-induced hemolysis[1][2].
Related CatalogSignaling Pathways >>Metabolic Enzyme/Protease >>PhospholipaseResearch Areas >>Inflammation/Immunology
Target

sPLA2

References

[1]. Hope WC, et al. Secretory phospholipase A2 inhibitors and calmodulin antagonists as inhibitors of cytosolic phospholipase A2. Agents Actions. 1993;39 Spec No:C39-42.  

[2]. Yang Zhe, et al. Oxygen-carrying bionic nano antidote and its preparation method and application in preparation of anti snake venom drug. China, CN113509488 A. 2021-10-19.

Chemical & Physical Properties

Molecular FormulaC25H52NO5P
Molecular Weight477.66
Exact Mass491.337585
PSA94.70000
LogP3.87
Storage condition?20°C

Synonyms

2-[(9Z)-9-Octadecenoyloxy]ethyl 2-(trimethylammonio)ethyl phosphate
Ethanaminium, 2-[[hydroxy[2-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]ethoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt
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