Introduction：Basic information about CAS 67605-85-0|N-Butanoyl-L-homoserine lactone, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | N-Butanoyl-L-homoserine lactone |
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| CAS Number | 67605-85-0 | Molecular Weight | 171.194 |
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| Density | 1.1±0.1 g/cm3 | Boiling Point | 428.1±34.0 °C at 760 mmHg |
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| Molecular Formula | C8H13NO3 | Melting Point | / |
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| MSDS | / | Flash Point | 212.7±25.7 °C |
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Names
| Name | N-[(3S)-2-oxooxolan-3-yl]butanamide |
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| Synonym | More Synonyms |
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N-Butanoyl-L-homoserine lactone BiologicalActivity
| Description | N-Butanoyl-L-homoserine lactone is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). N-Butanoyl-L-homoserine lactone has antibacterial activity and is used in antibacterial biofilm[1]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Antibody-drug Conjugate >>ADC LinkerSignaling Pathways >>Anti-infection >>Bacterial |
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| Target | Cleavable |
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| In Vitro | ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
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| References | [1]. Keith Alan Charlton, et al. Methods for the Treatment of an Infectious Bacterial Disease with an Anti-Lactone or Lactone Derived Signal Molecules Antibody. US20130045208A1 |
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Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
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| Boiling Point | 428.1±34.0 °C at 760 mmHg |
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| Molecular Formula | C8H13NO3 |
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| Molecular Weight | 171.194 |
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| Flash Point | 212.7±25.7 °C |
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| Exact Mass | 171.089539 |
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| PSA | 55.40000 |
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| LogP | -1.10 |
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| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
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| Index of Refraction | 1.476 |
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| InChIKey | VFFNZZXXTGXBOG-LURJTMIESA-N |
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| SMILES | CCCC(=O)NC1CCOC1=O |
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| Storage condition | 2-8°C |
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Synonyms
| C4-homoserine lactone |
| Butanamide, N-[(3S)-tetrahydro-2-oxo-3-furanyl]- |
| N-Butyryl-DL-homoserin-lacton |
| HL4 |
| N-Butyryl-L-homoserine lactone |
| N-[(3S)-2-oxotetrahydrofuran-3-yl]butanamide |
| (+)-a(S)-butyr-amido-r-butyrolactone |
| N-[(3S)-2-Oxotetrahydro-3-furanyl]butanamide |
| butanoyl homoserine lactone |
