CAS 124-20-9|spermidine
Introduction：Basic information about CAS 124-20-9|spermidine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | spermidine | ||
|---|---|---|---|
| CAS Number | 124-20-9 | Molecular Weight | 145.246 |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 246.6±8.0 °C at 760 mmHg |
| Molecular Formula | C7H19N3 | Melting Point | 23-25 °C |
| MSDS | ChineseUSA | Flash Point | 118.1±22.0 °C |
| Symbol | GHS05 | Signal Word | Danger |
Names
| Name | spermidine |
|---|---|
| Synonym | More Synonyms |
spermidine BiologicalActivity
| Description | Spermidine, a precursor of spermine, is a polyamine derived from putrescine and could help stabilize some membranes and nucleic acid structures. |
|---|---|
| Related Catalog | Research Areas >>Metabolic DiseaseNatural Products >>Others |
| Target | Human Endogenous Metabolite |
Chemical & Physical Properties
| Density | 0.9±0.1 g/cm3 |
|---|---|
| Boiling Point | 246.6±8.0 °C at 760 mmHg |
| Melting Point | 23-25 °C |
| Molecular Formula | C7H19N3 |
| Molecular Weight | 145.246 |
| Flash Point | 118.1±22.0 °C |
| Exact Mass | 145.157898 |
| PSA | 64.07000 |
| LogP | -0.84 |
| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
| Index of Refraction | 1.475 |
| InChIKey | ATHGHQPFGPMSJY-UHFFFAOYSA-N |
| SMILES | NCCCCNCCCN |
| Storage condition | 2-8°C |
| Stability | Stable, but air-sensitive and very hygroscopic - store under argon. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents. |
| Water Solubility | H2O: 1 M at 20 °C, clear, colorless |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD30 - Lethal Dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- >1 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD30 - Lethal Dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 450 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature decrease
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 78 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Bird - chicken
- DOSE/DURATION :
- 9504 gm/kg/14D-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Liver - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
MUTATION DATA - TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lung
- DOSE/DURATION :
- 200 mmol/L
- REFERENCE :
- IJRBA3 International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. (Taylor & Francis Inc., 242 Cherry St., Philadelphia, PA 19106) V.1- 1959- Volume(issue)/page/year: 9,185,1965
- TYPE OF TEST :
- DNA damage
- TEST SYSTEM :
- Mammal - species unspecified Lung
- DOSE/DURATION :
- 200 mmol/L
- REFERENCE :
- IJRBA3 International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine. (Taylor & Francis Inc., 242 Cherry St., Philadelphia, PA 19106) V.1- 1959- Volume(issue)/page/year: 9,185,1965
Safety Information
| Symbol | GHS05 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H314 |
| Precautionary Statements | P280-P305 + P351 + P338-P310 |
| Personal Protective Equipment | Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | C:Corrosive; |
| Risk Phrases | R34 |
| Safety Phrases | S26-S36/37/39-S45 |
| RIDADR | UN 2735 8/PG 2 |
| WGK Germany | 3 |
| RTECS | EJ7000000 |
| Packaging Group | III |
| Hazard Class | 8 |
| HS Code | 2921290000 |
Customs
| HS Code | 2921290000 |
|---|---|
| Summary | 2921290000 other acyclic polyamines and their derivatives; salts thereof。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
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Synonyms
| spermidine |
| N-(γ-aminopropyl)tetramethylenediamine |
| N-(3-Aminopropyl)butan-1,4-diamin |
| N'-(3-aminopropyl)butane-1,4-diamine |
| 1,8-Diamino-4-azaoctane (N-(3-Aminopropyl)-1,4-diaminobutane |
| Additive Screening |
| N1-(3-Aminopropyl)butane-1,4-diamine |
| N-(3-Aminopropyl)-4-aminobutylamine |
| N-(3-Aminopropyl)butane-1,4-diamine |
| MFCD00008229 |
| 1,4-Butanediamine, N-(3-aminopropyl)- |
| N-(3-Aminopropyl)-1,4-butanediamine |
| N-(g-Aminopropyl)tetramethylenediamine |
| EINECS 204-689-0 |
