CAS 70375-22-3|z-arg-amc hcl

Introduction：Basic information about CAS 70375-22-3|z-arg-amc hcl, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. z-arg-amc hcl BiologicalActivity
3. Chemical & Physical Properties
4. Safety Information
5. Synonyms

Common Name	z-arg-amc hcl
CAS Number	70375-22-3	Molecular Weight	501.96300
Density	/	Boiling Point	793ºC at 760 mmHg
Molecular Formula	C₂₄H₂₈ClN₅O₅	Melting Point	204-205ºC
MSDS	ChineseUSA	Flash Point	433.4ºC

Names

Name	benzyl N-[(2S)-5-(diaminomethylideneamino)-1-[(4-methyl-2-oxochromen-7-yl)amino]-1-oxopentan-2-yl]carbamate,hydrochloride
Synonym	More Synonyms

z-arg-amc hcl BiologicalActivity

Description	Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm)[1][2].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. Paczek L, et al. Trypsin, elastase, plasmin and MMP-9 activity in the serum during the human ageing process. Age Ageing. 2008 May;37(3):318-23. [2]. Brown A, et al. Necator americanus (human hookworm) aspartyl proteinases and digestion of skin macromolecules during skin penetration. Am J Trop Med Hyg. 1999 May;60(5):840-7.

Description

Z-Arg-AMC hydrochloride is a fluorogenic substrate for trypsin and papain. Z-Arg-AMC hydrochloride can be used to research activity of trypsin (Ex/Em=355/460 nm)[1][2].

Related Catalog

Research Areas >>OthersSignaling Pathways >>Others >>Others

References

[1]. Paczek L, et al. Trypsin, elastase, plasmin and MMP-9 activity in the serum during the human ageing process. Age Ageing. 2008 May;37(3):318-23.

[2]. Brown A, et al. Necator americanus (human hookworm) aspartyl proteinases and digestion of skin macromolecules during skin penetration. Am J Trop Med Hyg. 1999 May;60(5):840-7.

Chemical & Physical Properties

Boiling Point	793ºC at 760 mmHg
Melting Point	204-205ºC
Molecular Formula	C₂₄H₂₈ClN₅O₅
Molecular Weight	501.96300
Flash Point	433.4ºC
Exact Mass	501.17800
PSA	159.54000
LogP	5.05500
InChIKey	JYWCRDUTYUBXOL-FYZYNONXSA-N
SMILES	Cc1cc(=O)oc2cc(NC(=O)C(CCCN=C(N)N)NC(=O)OCc3ccccc3)ccc12.Cl
Storage condition	2-8°C
Water Solubility	DMF: soluble

Safety Information

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Safety Phrases	S22-S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3

Synonyms

Z-Arg-MCA

Z-L-Arginine-4-methyl-7-coumarinylamide hydrochloride

Carbobenzoxy-L-arginine-7-amino-4-methylcoumarin hydrochloride

EINECS 274-586-3

Nalpha-Cbz-L-arginine 7-amido-4-methylcoumarin hydrochloride

Z-L-Arg 7-amido-4-methylcoumarin hydrochloride

benzyl (S)-(4-(amidinoamino)-1-{[(4-methyl-2-oxo-2H-1-benzopyran-7-yl)amino]carbonyl}butyl)carbamate monohydrochloride

MFCD00039019

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