CAS 4099-35-8|S-(2-Aminoethyl)-L-cysteine hydrochloride

Introduction:Basic information about CAS 4099-35-8|S-(2-Aminoethyl)-L-cysteine hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameS-(2-Aminoethyl)-L-cysteine hydrochloride
CAS Number4099-35-8Molecular Weight200.68700
Density1.289g/cm3Boiling Point341.1ºC at 760 mmHg
Molecular FormulaC5H13ClN2O2SMelting Point/
MSDSChineseUSAFlash Point160.1ºC

Names

Names-(2-aminoethyl)-l-cysteine hydrochloride
SynonymMore Synonyms

BiologicalActivity

DescriptionThialysine (hydrochloride) is a cysteine derivative[1].
Related CatalogResearch Areas >>OthersSignaling Pathways >>Others >>Others
In VitroAmino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].
References

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807.

Chemical & Physical Properties

Density1.289g/cm3
Boiling Point341.1ºC at 760 mmHg
Molecular FormulaC5H13ClN2O2S
Molecular Weight200.68700
Flash Point160.1ºC
Exact Mass200.03900
PSA114.64000
LogP1.29280
Index of Refraction1.57
Storage condition2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
HA1690000
CHEMICAL NAME :
Cysteine, S-(2-aminoethyl)-, monohydrochloride, L-
CAS REGISTRY NUMBER :
4099-35-8
LAST UPDATED :
199712
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C5-H12-N2-O2-S.Cl-H
MOLECULAR WEIGHT :
200.71
WISWESSER LINE NOTATION :
Z2S1YZVQ &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FRXXBL French Demande Patent Document. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #2155776
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
300 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
WGK Germany3
RTECSHA1690000
HS Code2930909090

Customs

HS Code2930909090
Summary2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles26

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Evidence for conformational movement and radical mechanism in the reaction of 4-thia-L-lysine with lysine 5,6-aminomutase.

J. Phys. Chem. B 113(36) , 12161-3, (2009)

We demonstrate that the steady state reaction of lysine 5,6-aminomutase with substrate analogue 4-thia-l-lysine generates a radical intermediate, which accumulates in the enzyme to an electron paramag...

Radical triplets and suicide inhibition in reactions of 4-thia-D- and 4-thia-L-lysine with lysine 5,6-aminomutase.

Biochemistry 48(34) , 8151-60, (2009)

Lysine 5,6-aminomutase (5,6-LAM) catalyzes the interconversions of D- or L-lysine and the corresponding enantiomers of 2,5-diaminohexanoate, as well as the interconversion of L-beta-lysine and l-3,5-d...

Inhibition of lysine 2,3-aminomutase by the alternative substrate 4-thialysine and characterization of the 4-thialysyl radical intermediate.

Arch. Biochem. Biophys. 387(2) , 281-8, (2001)

Lysine 2,3-aminomutase catalyzes the interconversion of L-lysine and L-beta-lysine. 4-Thia-L-lysine (4-thialysine) is an alternative substrate for Lysine 2,3-aminomutase. The organic free radical that...

Synonyms

H-Cys(aminoethyl)-OH
H-CYS(ET-NH2)-OH HCL
S-(2-aminoethyl)-L-cysteine monohydrochloride
CYSTEINE(AMINOETHYL)-OH HCL
L-4-thialysine hydrochloride
MFCD00036385
usafxr-43
EINECS 223-862-1
S-(2-Amino-aethyl)-L-cystein,Hydrochlorid
S-(aminoethyl)-L-cysteine hydrochloride
thialysinehydrochloride
S-(2-amino-ethyl)-L-cysteine,hydrochloride
lj226
L-Thialysin Hydrochlorid
H-CYS(AMINOETHYL)-OH HCL
THIALSINE
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