CAS 1421-65-4|L-3,4-Dihydroxyphenylalanine Methyl ester hydrochloride
Introduction：Basic information about CAS 1421-65-4|L-3,4-Dihydroxyphenylalanine Methyl ester hydrochloride, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | L-3,4-Dihydroxyphenylalanine Methyl ester hydrochloride | ||
|---|---|---|---|
| CAS Number | 1421-65-4 | Molecular Weight | 247.676 |
| Density | 1.322g/cm3 | Boiling Point | 384.4ºC at 760mmHg |
| Molecular Formula | C10H14ClNO4 | Melting Point | / |
| MSDS | USA | Flash Point | 186.3ºC |
Names
| Name | L-DOPA Methyl Ester Hydrochloride |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.322g/cm3 |
|---|---|
| Boiling Point | 384.4ºC at 760mmHg |
| Molecular Formula | C10H14ClNO4 |
| Molecular Weight | 247.676 |
| Flash Point | 186.3ºC |
| Exact Mass | 247.061142 |
| PSA | 92.78000 |
| LogP | 1.64290 |
| Vapour Pressure | 1.86E-06mmHg at 25°C |
| InChIKey | WFGNJLMSYIJWII-FJXQXJEOSA-N |
| SMILES | COC(=O)C(N)Cc1ccc(O)c(O)c1.Cl |
| Storage condition | -20°C |
Safety Information
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2923900090 |
Customs
| HS Code | 2923900090 |
|---|---|
| Summary | 2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
Articles32
More Articles| Striatal astrocytes act as a reservoir for L-DOPA. PLoS ONE 9(9) , e106362, (2014) L-DOPA is therapeutically efficacious in patients with Parkinson's disease (PD), although dopamine (DA) neurons are severely degenerated. Since cortical astrocytes express neutral amino acid transport... | |
| L-DOPA-induced dyskinesia in a rat model of Parkinson's disease is associated with the fluctuational release of norepinephrine in the sensorimotor striatum. J. Neurosci. Res. 92(12) , 1733-45, (2014) L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia (LID) is the most common complication of standard L-DOPA therapy for Parkinson's disease experienced by most parkinsonian patients. LID is asso... | |
| Genome-wide microarray analysis identifies a potential role for striatal retrograde endocannabinoid signaling in the pathogenesis of experimental L-DOPA-induced dyskinesia. Synapse 68(8) , 332-43, (2014) l-3,4-Dihydroxyphenylalanine (L-DOPA) is the most widely used drug for the treatment of Parkinson's disease. Unfortunately, chronic administration of this dopamine precursor causes L-DOPA-induced dysk... |
Synonyms
| L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride |
| MFCD00038958 |
| L-Tyrosine, 3-hydroxy-, methyl ester, hydrochloride (1:1) |
| L-3,4-Dihydroxyphenylalanine methyl ester hydrochloride |
| methyl (2S)-2-amino-3-(3,4-dihydroxyphenyl)propanoate,hydrochloride |
| Methyl 3-hydroxy-L-tyrosinate hydrochloride (1:1) |
| (S)-Methyl 2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride |
| Methyl L-DOPA hydrochloride |
| methyldopa hydrochloride |
