CAS 4046-02-0|Ethyl ferulate
| Common Name | Ethyl ferulate | ||
|---|---|---|---|
| CAS Number | 4046-02-0 | Molecular Weight | 222.24 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 382.3±0.0 °C at 760 mmHg |
| Molecular Formula | C12H14O4 | Melting Point | 63-65 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 132.5±17.2 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | Ethyl 4'-hydroxy-3'-methoxycinnamate |
|---|---|
| Synonym | More Synonyms |
Ethyl ferulate BiologicalActivity
| Description | Ethyl ferulate, a naturally lipophilic derivative of ferulic acid originally derived from giant fennel (F. communis), induces heme oxygenase-1 (HO-1) and protects rat neurons against oxidative stress[1]. Ethyl ferulate also protects neurons against amyloid β peptide (1-42)-induced oxidative stress and neurotoxicity[2]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
| References | [1]. Scapagnini G, et al. Ethyl ferulate, a lipophilic polyphenol, induces HO-1 and protects rat neurons against oxidative stress. Antioxid Redox Signal. 2004 Oct;6(5):811-8. [2]. Sultana R, et al. Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity. J Neurochem. 2005 Feb;92(4):749-58. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 382.3±0.0 °C at 760 mmHg |
| Melting Point | 63-65 °C(lit.) |
| Molecular Formula | C12H14O4 |
| Molecular Weight | 222.24 |
| Flash Point | 132.5±17.2 °C |
| Exact Mass | 222.089203 |
| PSA | 55.76000 |
| LogP | 1.94 |
| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
| Index of Refraction | 1.566 |
| InChIKey | ATJVZXXHKSYELS-FNORWQNLSA-N |
| SMILES | CCOC(=O)C=Cc1ccc(O)c(OC)c1 |
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi:Irritant; |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S26-S37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 3 |
| HS Code | 2918990090 |
Customs
| HS Code | 2918990090 |
|---|---|
| Summary | 2918990090. other carboxylic acids with additional oxygen function and their anhydrides, halides, peroxides and peroxyacids; their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Articles26
More Articles| Soluble and cell wall-bound phenolic acids and ferulic acid dehydrodimers in rye flour and five bread model systems: insight into mechanisms of improved availability. J. Sci. Food Agric. 95(5) , 1103-15, (2015) The bread-making process influences bread components, including phenolics that significantly contribute to its antioxidant properties. Five bread model systems made from different rye cultivars were i... | |
| Hydroxycinnamic acid ethyl esters as precursors to ethylphenols in wine. J. Agric. Food Chem. 60(9) , 2293-8, (2012) A method for determining ethyl coumarate and ethyl ferulate in wine using GC-MS with deuterium-labeled analogues has been developed and used to measure the evolution of these two esters during the pro... | |
| Inhibitory effects of caffeic acid ethyl ester on H2O2-induced cytotoxicity and DNA single-strand breaks in Chinese hamster V79 cells. Biosci. Biotechnol. Biochem. 60(2) , 316-8, (1996) Cytotoxicity and DNA single-strand breaks caused by H2O2 were assessed by a colony formation assay and a DNA precipitation assay, respectively, with Chinese hamster V79 cells. In both assays, caffeic ... |
Synonyms
| ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate |
| MFCD00009190 |
| 4-Hydroxy-3-methoxycinnamic Acid Ethyl Ester |
| Ferulic acid ethyl ester |
| Ethyl 4-Hydroxy-3-MethoxycinnaMate |
| 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester |
| EINECS 223-745-5 |
| Ethyl Ferulate |
| Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate |
