Introduction:Basic information about CAS 127637-03-0|Histatin-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Histatin-8 |
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| CAS Number | 127637-03-0 | Molecular Weight | 1562.69000 |
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| Density | 1.54g/cm3 | Boiling Point | / |
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| Molecular Formula | C70H99N25O17 | Melting Point | / |
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| MSDS | USA | Flash Point | / |
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Names
| Name | h-lys-phe-his-glu-lys-his-his-ser-his-arg-gly-tyr-oh |
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| Synonym | More Synonyms |
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Histatin-8 BiologicalActivity
| Description | Histatin-8 is a part of the Histatin-3 central sequence and is known as hemagglutination-inhibiting peptide. Histatin-8 is a potent anti-fungal peptide. Histatin-8 shows antimicrobial activity against yeast strains. Histatin-8 can be used for oral thrush research[1][2]. |
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| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal |
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| In Vitro | Histatin-8 can inhibit the growth of both sensitive standard strain and colistin-resistant mutant of A. baumannii ATCC 19606 at 32 μg/mL[1]. |
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Chemical & Physical Properties
| Density | 1.54g/cm3 |
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| Molecular Formula | C70H99N25O17 |
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| Molecular Weight | 1562.69000 |
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| Exact Mass | 1561.77000 |
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| PSA | 689.84000 |
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| LogP | 1.38680 |
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| Index of Refraction | 1.709 |
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| InChIKey | MSVLPSBDYOVCST-ZUDWGGBQSA-N |
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| SMILES | N=C(N)NCCCC(NC(=O)C(CC1C=NC=N1)NC(=O)C(CO)NC(=O)C(CC1C=NC=N1)NC(=O)C(CC1C=NC=N1)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CC1C=NC=N1)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCCN)C(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)O |
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Safety Information
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
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| RIDADR | NONH for all modes of transport |
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Synonyms
| Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr |
| inyl-glycyl-tyrosine |
| KFHEKHHSHRGY |
| LYS-PHE-HIS-GLU-LYS-HIS-HIS-SER-HIS-ARG-GLY-TYR |
| HISTATIN-8 |
| L-F-H-E-K-H-H-S-H-R-G-Y |
| HIP |