CAS 127637-03-0|Histatin-8

Introduction:Basic information about CAS 127637-03-0|Histatin-8, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameHistatin-8
CAS Number127637-03-0Molecular Weight1562.69000
Density1.54g/cm3Boiling Point/
Molecular FormulaC70H99N25O17Melting Point/
MSDSUSAFlash Point/

Names

Nameh-lys-phe-his-glu-lys-his-his-ser-his-arg-gly-tyr-oh
SynonymMore Synonyms

Histatin-8 BiologicalActivity

DescriptionHistatin-8 is a part of the Histatin-3 central sequence and is known as hemagglutination-inhibiting peptide. Histatin-8 is a potent anti-fungal peptide. Histatin-8 shows antimicrobial activity against yeast strains. Histatin-8 can be used for oral thrush research[1][2].
Related CatalogResearch Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal
In VitroHistatin-8 can inhibit the growth of both sensitive standard strain and colistin-resistant mutant of A. baumannii ATCC 19606 at 32 μg/mL[1].

Chemical & Physical Properties

Density1.54g/cm3
Molecular FormulaC70H99N25O17
Molecular Weight1562.69000
Exact Mass1561.77000
PSA689.84000
LogP1.38680
Index of Refraction1.709
InChIKeyMSVLPSBDYOVCST-ZUDWGGBQSA-N
SMILESN=C(N)NCCCC(NC(=O)C(CC1C=NC=N1)NC(=O)C(CO)NC(=O)C(CC1C=NC=N1)NC(=O)C(CC1C=NC=N1)NC(=O)C(CCCCN)NC(=O)C(CCC(=O)O)NC(=O)C(CC1C=NC=N1)NC(=O)C(Cc1ccccc1)NC(=O)C(N)CCCCN)C(=O)NCC(=O)NC(Cc1ccc(O)cc1)C(=O)O

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport

Synonyms

Lys-Phe-His-Glu-Lys-His-His-Ser-His-Arg-Gly-Tyr
inyl-glycyl-tyrosine
KFHEKHHSHRGY
LYS-PHE-HIS-GLU-LYS-HIS-HIS-SER-HIS-ARG-GLY-TYR
HISTATIN-8
L-F-H-E-K-H-H-S-H-R-G-Y
HIP
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