Introduction：Basic information about CAS 219138-08-6|Z-Val-Asp-Val-Ala-Asp-AFC, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Z-Val-Asp-Val-Ala-Asp-AFC |
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| CAS Number | 219138-08-6 | Molecular Weight | 862.80 |
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| Density | / | Boiling Point | / |
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| Molecular Formula | C39H45F3N6O13 | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | z-vdvad-afc |
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| Synonym | More Synonyms |
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Z-Val-Asp-Val-Ala-Asp-AFC BiologicalActivity
| Description | Z-VDVAD-AFC is a fluorogenic substrate. Z-VDVAD-AFC is used to measure the activity of cysteine protease 3 (Caspase-3). Z-VDVAD-AFC undergoes hydrolysis to release 7-amino-4-trifluoromethylcoumarin (AFC). AFC is fluorescent under ultraviolet light and can emit fluorescent signals[1]. |
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| Related Catalog | Research Areas >>Others |
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| References | [1]. Pallepati P, et, al. Mild thermotolerance induced at 40°C protects HeLa cells against activation of death receptor-mediated apoptosis by hydrogen peroxide. Free Radic Biol Med. 2011 Mar 15;50(6):667-79. |
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Chemical & Physical Properties
| Molecular Formula | C39H45F3N6O13 |
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| Molecular Weight | 862.80 |
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| Exact Mass | 862.30000 |
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| PSA | 288.64000 |
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| LogP | 4.29330 |
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| Storage condition | -15°C |
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Synonyms
| Z-Val-Asp-Ala-Asp-AFC |
| PASE-2 SUBSTRATE I,FLUOROGENIC |
| Z-VAL-ASP-VAL-ALA-ASP-AFC |
