Introduction：Basic information about CAS 73024-95-0|Met-Enkephalin-Arg-Phe, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Met-Enkephalin-Arg-Phe |
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| CAS Number | 73024-95-0 | Molecular Weight | 877.02 |
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| Density | 1.38g/cm3 | Boiling Point | / |
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| Molecular Formula | C42H56N10O9S | Melting Point | / |
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| MSDS | / | Flash Point | / |
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Names
| Name | met-enkephalin-arg-phe |
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| Synonym | More Synonyms |
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Met-Enkephalin-Arg-Phe BiologicalActivity
| Description | Met-Enkephalin-Arg-Phe is a naturally occurring heptapeptide with analgesic activity[1]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Neurological Disease |
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| In Vivo | Met-Enkephalin-Arg-Phe (10-100 nmol/mouse; i.c.v.; once) 在小鼠中有缓解疼痛活性[1]。 Animal Model: Male Swiss Webster mice[1] Dosage: 10-100 nmol/mouse Administration: Intracerebralventricular injection, once Result: Produced a dose-related inhibition of the tail-flick response. The effects peaked at 2-4 min and were dissipated by 10 min. The EC50 was 38.5 nmol/mouse. |
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| References | [1]. Inturrisi CE, et al. Analgesic activity of the naturally occurring heptapeptide [Met]enkephalin-Arg6-Phe7. Proc Natl Acad Sci U S A. 1980 Sep;77(9):5512-4. |
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Chemical & Physical Properties
| Density | 1.38g/cm3 |
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| Molecular Formula | C42H56N10O9S |
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| Molecular Weight | 877.02 |
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| Exact Mass | 876.39500 |
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| PSA | 345.35000 |
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| LogP | 3.25660 |
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| Index of Refraction | 1.65 |
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| InChIKey | KTQKWSPZOZKAEE-LJADHVKFSA-N |
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| SMILES | CSCCC(NC(=O)C(Cc1ccccc1)NC(=O)CNC(=O)CNC(=O)C(N)Cc1ccc(O)cc1)C(=O)NC(CCCN=C(N)N)C(=O)NC(Cc1ccccc1)C(=O)O |
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Synonyms
| MERF |
| TYR-GLY-GLY-PHE-MET-ARG-PHE |
| METHIONINE ENKEPHALIN-ARG,PHE |
| Tyr-Gly-Gly-Phe-Met-Arg-Phe-OH |
| Met-Enkephalin-Arg-Phe MERF |
