Introduction：Basic information about CAS 957-56-2|Fluindione, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Fluindione |
|---|
| CAS Number | 957-56-2 | Molecular Weight | 240.23 |
|---|
| Density | 1.335g/cm3 | Boiling Point | 406.3ºC at 760mmHg |
|---|
| Molecular Formula | C15H9FO2 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 154.5ºC |
|---|
Names
| Name | 2-(4-fluorophenyl)indene-1,3-dione |
|---|
| Synonym | More Synonyms |
|---|
Fluindione BiologicalActivity
| Description | Fluindione is a inhibitor of 5-lipoxygenase with the IC50 of 15 μM. Fluindione has antiinflammatory activity[1]. |
|---|
| Related Catalog | Research Areas >>Inflammation/ImmunologySignaling Pathways >>Metabolic Enzyme/Protease >>5-Lipoxygenase |
|---|
| References | [1]. Brooks, et al. Structural analysis of 2-aryl-1,3-dione compounds as inhibitors of 5-lipoxygenase. Bioorganic & Medicinal Chemistry Letters, 2(10), 1309–1314. |
|---|
Chemical & Physical Properties
| Density | 1.335g/cm3 |
|---|
| Boiling Point | 406.3ºC at 760mmHg |
|---|
| Molecular Formula | C15H9FO2 |
|---|
| Molecular Weight | 240.23 |
|---|
| Flash Point | 154.5ºC |
|---|
| Exact Mass | 240.05900 |
|---|
| PSA | 34.14000 |
|---|
| LogP | 2.98850 |
|---|
| Index of Refraction | 1.619 |
|---|
| InChIKey | NASXCEITKQITLD-UHFFFAOYSA-N |
|---|
| SMILES | O=C1c2ccccc2C(=O)C1c1ccc(F)cc1 |
|---|
Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- NK5700000
- CHEMICAL NAME :
- 1,3-Indandione, 2-(p-fluorophenyl)-
- CAS REGISTRY NUMBER :
- 957-56-2
- BEILSTEIN REFERENCE NO. :
- 2052411
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C15-H9-F-O2
- MOLECULAR WEIGHT :
- 240.24
- WISWESSER LINE NOTATION :
- L56 BV DV CHJ CR DF
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 240 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- MPHEAE Medicina et Pharmacologia Experimentalis. (Basel, Switzerland) V.12-17, 1965-67. For publisher information, see PHMGBN. Volume(issue)/page/year: 17,497,1967
|
Safety Information
| RIDADR | UN 2811 |
|---|
| Packaging Group | III |
|---|
| Hazard Class | 6.1(b) |
|---|
| HS Code | 2914700090 |
|---|
Customs
| HS Code | 2914700090 |
|---|
| Summary | HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0% |
|---|
Synonyms
| 2-(4-Fluor-phenyl)-indandion-(1,3) |
| 1H-Indene-1,3(2H)-dione,2-(4-fluorophenyl) |
| Fluindione |
| Fluindionum [INN-Latin] |
| Fluindione [INN] |
| 2-(4-fluoro-phenyl)-indan-1,3-dione |
| 2-(p-Fluorophenyl)-1,3-indandione |
| Previscan |
| Fluindiona [INN-Spanish] |
| LM 123 |
| 2-(4-Fluor-phenyl)-indan-1,3-dion |
| 2-(4-fluorophenyl)-1,3-indanedione |
