CAS 86259-87-2|Tetraethylene Glycol Monobenzyl Ether

Introduction：Basic information about CAS 86259-87-2|Tetraethylene Glycol Monobenzyl Ether, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameTetraethylene Glycol Monobenzyl Ether
CAS Number86259-87-2Molecular Weight284.348
Density1.1±0.1 g/cm3Boiling Point398.7±32.0 °C at 760 mmHg
Molecular FormulaC15H24O5Melting Point/
MSDS/Flash Point194.9±25.1 °C

Names

NameTetraethylene Glycol Monobenzyl Ether
SynonymMore Synonyms

Tetraethylene Glycol Monobenzyl Ether BiologicalActivity

DescriptionBnO-PEG4-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related CatalogSignaling Pathways >>PROTAC >>PROTAC Linker
Target

PEGs

In VitroPROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Andrew P. Crew, et al. Tau-protein targeting protacs and associated methods of use. Patent. US20180125821A1.

Chemical & Physical Properties

Density1.1±0.1 g/cm3
Boiling Point398.7±32.0 °C at 760 mmHg
Molecular FormulaC15H24O5
Molecular Weight284.348
Flash Point194.9±25.1 °C
Exact Mass284.162384
PSA57.15000
LogP0.18
Vapour Pressure0.0±1.0 mmHg at 25°C
Index of Refraction1.500
InChIKeyQDPIVUQXPXUNLN-UHFFFAOYSA-N
SMILESOCCOCCOCCOCCOCc1ccccc1

Safety Information

HS Code2909499000

Customs

HS Code2909499000
Summary2909499000. ether-alcohols and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

Synonyms

1-Phenyl-2,5,8,11-tetraoxatridecan-13-ol
2-[2-[2-(2-phenylmethoxyethoxy)ethoxy]ethoxy]ethanol
2,5,8,11-Tetraoxatridecan-13-ol, 1-phenyl-
Benzyl-PEG4-alcohol
BnO-PEG4-OH
CAS 845266-20-8|3-[(2-THIENYLTHIO)METHYL]BENZOIC ACID
CAS 310395-15-4|4-(5-BENZOFURANYL)-PIPERIDINE
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