CAS 115-69-5|2-Amino-2-methyl-1,3-propanediol

Introduction：Basic information about CAS 115-69-5|2-Amino-2-methyl-1,3-propanediol, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. 2-Amino-2-methyl-1,3-propanediol BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles18
8. Synonyms

Common Name	2-Amino-2-methyl-1,3-propanediol
CAS Number	115-69-5	Molecular Weight	105.136
Density	1.1±0.1 g/cm3	Boiling Point	271.5±0.0 °C at 760 mmHg
Molecular Formula	C₄H₁₁NO₂	Melting Point	100-110 °C(lit.)
MSDS	ChineseUSA	Flash Point	109.7±21.8 °C
Symbol	GHS05, GHS07	Signal Word	Warning

Names

Name	2-amino-2-methylpropane-1,3-diol
Synonym	More Synonyms

2-Amino-2-methyl-1,3-propanediol BiologicalActivity

Description	2-Amino-2-methyl-1,3-propanediol is a solid-solid phase change materials (PCMs). Amino-2-methyl-1,3-propanediol can be used to make surfactants, vulcanization accelerators and as a biological buffer[1].
Related Catalog	Research Areas >>OthersSignaling Pathways >>Others >>Others
References	[1]. RyoheiGotoh, et al. Controlling heat release of crystallization from supercooling state of a solid-solid PCM, 2-amino-2-methyl-1,3-propanediol. International Journal of Heat and Mass Transfer, 2019, 1132-1140.

Chemical & Physical Properties

Density	1.1±0.1 g/cm3
Boiling Point	271.5±0.0 °C at 760 mmHg
Melting Point	100-110 °C(lit.)
Molecular Formula	C₄H₁₁NO₂
Molecular Weight	105.136
Flash Point	109.7±21.8 °C
Exact Mass	105.078979
PSA	66.48000
LogP	-1.16
Vapour density	3.63 (vs air)
Vapour Pressure	0.0±1.2 mmHg at 25°C
Index of Refraction	1.494
InChIKey	UXFQFBNBSPQBJW-UHFFFAOYSA-N
SMILES	CC(N)(CO)CO
Stability	Stable. Combustible. May be moisture-sensitive. Incompatible with strong oxidizing agents, copper, aluminium, brass, strong acids.
Water Solubility	2500 g/L (20 ºC)

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TY2975000

CHEMICAL NAME :: 1,3-Propanediol, 2-amino-2-methyl-

CAS REGISTRY NUMBER :: 115-69-5

BEILSTEIN REFERENCE NO. :: 0635708

LAST UPDATED :: 199701

DATA ITEMS CITED :: 6

MOLECULAR FORMULA :: C4-H11-N-O2

MOLECULAR WEIGHT :: 105.16

WISWESSER LINE NOTATION :: Q1XZ1&1Q

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 17 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JACTDZ Journal of the American College of Toxicology. (Mary Ann Liebert, Inc., 1651 Third Ave., New York, NY 10128) V.1-12, 1982-1993. Discontinued. Volume(issue)/page/year: 9(2),203,1990

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AECTCV Archives of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 070944) V.1- 1973- Volume(issue)/page/year: 14,111,1985

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1500 mg/kg

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness Behavioral - coma

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 22,315,1940 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 82132 No. of Facilities: 38 (estimated) No. of Industries: 2 No. of Occupations: 2 No. of Employees: 66 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 82132 No. of Facilities: 663 (estimated) No. of Industries: 2 No. of Occupations: 7 No. of Employees: 7513 (estimated) No. of Female Employees: 5523 (estimated)

Safety Information

Symbol	GHS05, GHS07
Signal Word	Warning
Hazard Statements	H290-H315-H319-H335
Precautionary Statements	P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313
Personal Protective Equipment	dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes	Xi:Irritant;
Risk Phrases	R36/37/38
Safety Phrases	S26-S36-S37/39
RIDADR	UN 3259 8/PG 2
WGK Germany	1
RTECS	TY2975000
Hazard Class	8.0
HS Code	29221980

Customs

HS Code	29221980

Articles18

Immunophenotype and gene expression profile of mesenchymal stem cells derived from canine adipose tissue and bone marrow.

Vet. Immunol. Immunopathol. 161(1-2) , 21-31, (2014)

Veterinary adult stem cell therapy is an emerging area of basic and clinical research. Like their human counterparts, veterinary mesenchymal stem cells (MSCs) offer many potential therapeutic benefits...

Gliotoxin potentiates osteoblast differentiation by inhibiting nuclear factor-κB signaling.

Mol. Med. Report. 12 , 877-84, (2015)

The differentiation of pluripotent mesenchymal stem cells to mature osteoblasts is crucial for the maintenance of the adult skeleton. In rheumatic arthritis, osteoblast differentiation is impaired by ...

Final amended report on safety assessment on aminomethyl propanol and aminomethyl propanediol.

Int. J. Toxicol. 28(6 Suppl) , 141S-61S, (2009)

Aminomethyl propanol and aminomethyl propanediol are substituted aliphatic alcohols that function as pH adjusters in cosmetic products at concentrations less than 10%; additionally, aminomethyl propan...

Synonyms

AMPD,Ammediol

1,3-Propanediol, 2-amino-2-methyl-

2-amino-2-methylpropane-1,3-diol

2-Amino-2-methyl-1,3-propanediol

EINECS 204-100-7

MFCD00004678

Recommended......