CAS 5571-97-1|2-(3,4-dichlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one

Introduction：Basic information about CAS 5571-97-1|2-(3,4-dichlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Chemical & Physical Properties
3. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
4. Synonyms

Common Name	2-(3,4-dichlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one
CAS Number	5571-97-1	Molecular Weight	308.18100
Density	1.476g/cm3	Boiling Point	555.4ºC at 760 mmHg
Molecular Formula	C₁₁H₁₁Cl₂NO₃S	Melting Point	/
MSDS	/	Flash Point	289.7ºC

Names

Name	2-(3,4-dichlorophenyl)-3-methyl-1,1-dioxo-1,3-thiazinan-4-one
Synonym	More Synonyms

Chemical & Physical Properties

Density	1.476g/cm3
Boiling Point	555.4ºC at 760 mmHg
Molecular Formula	C₁₁H₁₁Cl₂NO₃S
Molecular Weight	308.18100
Flash Point	289.7ºC
Exact Mass	306.98400
PSA	62.83000
LogP	3.28760
Index of Refraction	1.588
InChIKey	FTBWWORDOHNJDB-UHFFFAOYSA-N
SMILES	CN1C(=O)CCS(=O)(=O)C1c1ccc(Cl)c(Cl)c1

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XJ1225000

CHEMICAL NAME :: 4H-1,3-Thiazin-4-one, 2-(3,4-dichlorophenyl)tetrahydro-3-methyl-, 1,1-dioxide

CAS REGISTRY NUMBER :: 5571-97-1

LAST UPDATED :: 199206

DATA ITEMS CITED :: 7

MOLECULAR FORMULA :: C11-H11-Cl2-N-O3-S

MOLECULAR WEIGHT :: 308.19

WISWESSER LINE NOTATION :: T6VN DSWTJ B1 CR CG DG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1050 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,168,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 840 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - flaccid paralysis without anesthesia (usually neuromuscular blockage) Behavioral - ataxia

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 122,517,1957

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 570 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,168,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,168,1959

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 400 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,168,1959 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 3975 mg/kg/5D-C

TOXIC EFFECTS :: Related to Chronic Data - death

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,168,1959

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 14445 mg/kg/54W-I

TOXIC EFFECTS :: Behavioral - tremor Behavioral - changes in motor activity (specific assay) Behavioral - ataxia

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 1,168,1959

Synonyms

Dichlormethazanone

2-(3,4-Dichlorophenyl)-3-methyl-4-metathiazanone 1,1-dioxide

(-)-2-(3,4-Dichlorphenyl)-tetrahydro-3-methyl-4H-1,3-thiazin-4-on-1,1-dioxid

Dichlormezanonum [INN-Latin]

Diclormezanona [INN-Spanish]

2-(3,4-dichlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide

Dichlormezanone

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