CAS 1139-30-6|Caryophyllene oxide
Introduction：Basic information about CAS 1139-30-6|Caryophyllene oxide, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Caryophyllene oxide | ||
|---|---|---|---|
| CAS Number | 1139-30-6 | Molecular Weight | 220.350 |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 279.7±19.0 °C at 760 mmHg |
| Molecular Formula | C15H24O | Melting Point | 62-63ºC(lit.) |
| MSDS | ChineseUSA | Flash Point | 119.7±19.5 °C |
| Symbol | GHS07 | Signal Word | Warning |
Names
| Name | (-)-Caryophyllene oxide |
|---|---|
| Synonym | More Synonyms |
Caryophyllene oxide BiologicalActivity
| Description | Caryophyllene oxide, isolated from from Annona squamosa L. bark., possesses analgesic and anti-inflammatory activity[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
| References | [1]. Chavan MJ, et al. Analgesic and anti-inflammatory activity of Caryophyllene oxide from Annona squamosa L. bark. Phytomedicine. 2010 Feb;17(2):149-51. |
Chemical & Physical Properties
| Density | 1.0±0.1 g/cm3 |
|---|---|
| Boiling Point | 279.7±19.0 °C at 760 mmHg |
| Melting Point | 62-63ºC(lit.) |
| Molecular Formula | C15H24O |
| Molecular Weight | 220.350 |
| Flash Point | 119.7±19.5 °C |
| Exact Mass | 220.182709 |
| PSA | 12.53000 |
| LogP | 4.57 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.507 |
| InChIKey | NVEQFIOZRFFVFW-RGCMKSIDSA-N |
| SMILES | C=C1CCC2OC2(C)CCC2C1CC2(C)C |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 21,661,1983
Safety Information
| Symbol | GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319 |
| Precautionary Statements | P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| Risk Phrases | R36/38 |
| Safety Phrases | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | 2 |
| RTECS | RP5530000 |
| HS Code | 29109000 |
Articles5
More Articles| Antiparasitic compounds from Cupania cinerea with activities against Plasmodium falciparum and Trypanosoma brucei rhodesiense. J. Nat. Prod. 74 , 559-66, (2011) In a survey of plants from Ecuador with antiprotozoal activity, Cupania cinerea was found to show significant in vitro activity against the Plasmodium falciparum K1 strain and Trypanosoma brucei rhode... | |
| Microbial transformation and butyrylcholinesterase inhibitory activity of (-)-caryophyllene oxide and its derivatives. J. Nat. Prod. 69 , 1429-34, (2006) Microbial transformation of the sesquiterpene (-)-caryophyllene oxide (1) [(1R,4R,5R,9S)-4,5-epoxycaryophyllan-8(13)-ene] by a number of fungi, using a standard two-stage fermentation technique, has a... | |
| H.M.R. Hoffmann, U. Vogt Synlett , 581, (1990) |
Synonyms
| (1R,4R,6R,10S)-4,12,12-trimethyl-9-methylene-5-oxatricyclo[8.2.0.04,6]dodecane |
| (-)-b-Caryophyllene oxide |
| 6,7-Epoxy-3(15)-caryophyllene |
| (−)-Caryophyllene oxide |
| 4b,5a-Epoxycaryophyllene |
| (-)-b-Caryophyllene epoxide |
| (1R,4R,6R,10S)-4,12,12-Trimethyl-9-methylene-5-oxatricyclo[8.2.0.0]dodecane |
| (-)-Epoxydihydrocaryophyllene |
| (-)-caryophyllene oxide |
| 5-Oxatricyclo(8.2.0.0(4,6))dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- |
| b-Caryophyllene oxide |
| Caryophyllene 4b,5a-oxide |
| β-Caryophyllene oxide |
| EINECS 214-519-7 |
| MFCD00134216 |
| b-Caryophyllene epoxide |
| trans-caryophyllene oxide |
| 5-Oxatricyclo[8.2.0.0]dodecane, 4,12,12-trimethyl-9-methylene-, (1R,4R,6R,10S)- |
| caryophyllene oxide |
| (−)-Epoxycaryophyllene |
