CAS 542-32-5|α-Aminoadipic acid

Introduction:Basic information about CAS 542-32-5|α-Aminoadipic acid, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Nameα-Aminoadipic acid
CAS Number542-32-5Molecular Weight161.156
Density1.3±0.1 g/cm3Boiling Point364.0±32.0 °C at 760 mmHg
Molecular FormulaC6H11NO4Melting Point196-198ºC
MSDSUSAFlash Point173.9±25.1 °C
Symbol
GHS07
Signal WordWarning

Names

Name2-aminoadipic acid
SynonymMore Synonyms

α-Aminoadipic acid BiologicalActivity

DescriptionAminoadipic acid is an intermediate in the metabolism of lysine and saccharopine.
Related CatalogNatural Products >>Acids and AldehydesResearch Areas >>Others
Target

Human Endogenous Metabolite

References

[1]. Wang TJ, et al. 2-Aminoadipic acid is a biomarker for diabetes risk. J Clin Invest. 2013 Oct;123(10):4309-17.

[2]. Wang X, et al. α-Aminoadipic acid protects against retinal disruption through attenuating Müller cell gliosis in a rat model of acute ocular hypertension. Drug Des Devel Ther. 2016 Oct 20;10:3449-3457.

Chemical & Physical Properties

Density1.3±0.1 g/cm3
Boiling Point364.0±32.0 °C at 760 mmHg
Melting Point196-198ºC
Molecular FormulaC6H11NO4
Molecular Weight161.156
Flash Point173.9±25.1 °C
Exact Mass161.068802
PSA100.62000
LogP-0.54
Vapour Pressure0.0±1.7 mmHg at 25°C
Index of Refraction1.515
InChIKeyOYIFNHCXNCRBQI-UHFFFAOYSA-N
SMILESNC(CCCC(=O)O)C(=O)O
Storage condition2-8°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MO1852000
CHEMICAL NAME :
Hexanedioic acid, 2-amino-
CAS REGISTRY NUMBER :
542-32-5
BEILSTEIN REFERENCE NO. :
1773077
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C6-H11-N-O4
MOLECULAR WEIGHT :
161.18

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 5,108,1960

Safety Information

Symbol
GHS07
Signal WordWarning
Hazard StatementsH317
Precautionary StatementsP280
Hazard CodesXi
Risk PhrasesR36/37/38
Safety PhrasesS24/25
RIDADRNONH for all modes of transport
WGK Germany3
RTECSMO1852000
HS Code2922499990

Customs

HS Code2922499990
SummaryHS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles54

More Articles
Impact of gluconic fermentation of strawberry using acetic acid bacteria on amino acids and biogenic amines profile.

Food Chem. 178 , 221-8, (2015)

This paper studies the amino acid profile of beverages obtained through the fermentation of strawberry purée by a surface culture using three strains belonging to different acetic acid bacteria specie...

Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.

Nature 457(7231) , 910-4, (2009)

Multiple, complex molecular events characterize cancer development and progression. Deciphering the molecular networks that distinguish organ-confined disease from metastatic disease may lead to the i...

Comparative metabolomics analysis on invigorating blood circulation for herb pair Gui-Hong by ultra-high-performance liquid chromatography coupled to quadrupole time-of-flight mass spectrometry and pattern recognition approach.

J. Pharm. Biomed. Anal. 107 , 456-63, (2015)

The compatibility of Angelicae Sinensis Radix (Danggui, DG) and Flos Carthami (Honghua, HH), a famous herb pair Gui-Hong (GH), can produce synergistic and promoting blood effects. Although some physio...

Synonyms

2-Aminohexanedioic acid
2-aminoadipic acid
AAD
DL-2-Aminohexanedioic acid
Hexanedioic acid, 2-amino-, (2R)-
D-2-Aminoadipic Acid
Hexanedioic acid, 2-amino-
α-Amino-adipic acid
.α.-Aminoadipic acid
UNII:1K7B1OED4N
DL-2-Aminoadipic acid
DL-a-aminoadipic acid
a-Aminoadipic acid
(2R)-2-Aminohexanedioic acid
MFCD00063119
(±)-2-Aminoadipic acid
EINECS 208-809-2
CAS 627-75-8|H-D-Arg-OH.HCl
CAS 602-60-8|9-Nitroanthracene
Recommended......
TOP