CAS 851518-71-3|1-(4-HYDROXYPHENYL)-5-METHYLPYRIDIN-2(1H)-ONE

Introduction:Basic information about CAS 851518-71-3|1-(4-HYDROXYPHENYL)-5-METHYLPYRIDIN-2(1H)-ONE, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name1-(4-HYDROXYPHENYL)-5-METHYLPYRIDIN-2(1H)-ONE
CAS Number851518-71-3Molecular Weight201.22100
Density/Boiling Point/
Molecular FormulaC12H11NO2Melting Point161-162 °C
MSDS/Flash Point/

Names

Name1-(4-hydroxyphenyl)-5-methylpyridin-2-one
SynonymMore Synonyms

BiologicalActivity

DescriptionHydronidone is a pyridine derivative and an antifibrotic agent for hepatic fibrosis[1].
References

[1]. Liu Y, et al. Tolerability and Pharmacokinetics of Hydronidone, an Antifibrotic Agent for Hepatic Fibrosis, after Single and Multiple Doses in Healthy Subjects: an Open-Label, Randomized, Dose-Escalating, First-in-Human Study. Eur J Drug Metab Pharmacokinet. 2017;42(1):37-48.

Chemical & Physical Properties

Melting Point161-162 °C
Molecular FormulaC12H11NO2
Molecular Weight201.22100
Exact Mass201.07900
PSA42.23000
LogP1.85150
InChIKeyNETTXQJYJRFTFS-UHFFFAOYSA-N
SMILESCc1ccc(=O)n(-c2ccc(O)cc2)c1

Safety Information

HS Code2933399090

Customs

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Synonyms

MFCD07369446
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