Introduction：Basic information about CAS 111-01-3|Squalane, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Squalane |
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| CAS Number | 111-01-3 | Molecular Weight | 422.813 |
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| Density | 0.8±0.1 g/cm3 | Boiling Point | 470.3±0.0 °C at 760 mmHg |
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| Molecular Formula | C30H62 | Melting Point | −38 °C(lit.) |
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| MSDS | ChineseUSA | Flash Point | 217.8±0.0 °C |
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Names
| Name | 2,6,10,15,19,23-hexamethyltetracosane |
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| Synonym | More Synonyms |
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Squalane BiologicalActivity
| Description | Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[1]. |
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| Related Catalog | Research Areas >>CancerSignaling Pathways >>Others >>Others |
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| In Vitro | Squalane exhibits a huge potential in nutraceutical and pharmaceutical industries. Squalane shows anticancer, antioxidant, drug carrier, detoxifier, skin hydrating, and emollient activities have been reported both in animal models and in vitro environments[1]. |
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| References | [1]. Kim SK, et al. Biological importance and applications of squalene and squalane. Adv Food Nutr Res. 2012;65:223-33. |
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Chemical & Physical Properties
| Density | 0.8±0.1 g/cm3 |
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| Boiling Point | 470.3±0.0 °C at 760 mmHg |
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| Melting Point | −38 °C(lit.) |
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| Molecular Formula | C30H62 |
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| Molecular Weight | 422.813 |
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| Flash Point | 217.8±0.0 °C |
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| Exact Mass | 422.485138 |
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| LogP | 15.59 |
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| Vapour Pressure | 0.0±0.5 mmHg at 25°C |
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| Index of Refraction | 1.448 |
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| InChIKey | PRAKJMSDJKAYCZ-UHFFFAOYSA-N |
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| SMILES | CC(C)CCCC(C)CCCC(C)CCCCC(C)CCCC(C)CCCC(C)C |
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| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- XB6070000
- CHEMICAL NAME :
- Tetracosane, 2,6,10,15,19,23-hexamethyl-
- CAS REGISTRY NUMBER :
- 111-01-3
- BEILSTEIN REFERENCE NO. :
- 0776019
- LAST UPDATED :
- 199709
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C30-H62
- MOLECULAR WEIGHT :
- 422.92
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- CTOIDG Cosmetics and Toiletries. (Allured Pub. Corp., POB 318, Wheaton, IL 60189) V.91- 1976- Volume(issue)/page/year: 94(8),41,1979 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84063 No. of Facilities: 109 (estimated) No. of Industries: 3 No. of Occupations: 10 No. of Employees: 20918 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84063 No. of Facilities: 1980 (estimated) No. of Industries: 11 No. of Occupations: 32 No. of Employees: 149812 (estimated) No. of Female Employees: 126648 (estimated)
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Safety Information
| Personal Protective Equipment | Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
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| Hazard Codes | Xi:Irritant; |
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| Risk Phrases | R36/37/38 |
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| Safety Phrases | S26-S36 |
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| RIDADR | NONH for all modes of transport |
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| WGK Germany | 3 |
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| RTECS | XB6070000 |
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| HS Code | 2901100000 |
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Customs
| HS Code | 2901100000 |
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| Summary | 2901100000 saturated acyclic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0% |
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Articles27
More Articles
| Biological importance and applications of squalene and squalane. Adv. Food Nutr. Res. 65 , 223-33, (2012) Squalene is a polyunsaturated hydrocarbon with a formula of C₃₀H₅₀. Squalene can be found in certain fish oils, especially shark liver oil, in high amounts and some vegetable oils in relatively smalle... | |
| How membrane permeation is affected by donor delivery solvent. Phys. Chem. Chem. Phys. 14(44) , 15525-38, (2012) We investigate theoretically and experimentally how the rate and extent of membrane permeation is affected by switching the donor delivery solvent from water to squalane for different permeants and me... | |
| Effects of squalene/squalane on dopamine levels, antioxidant enzyme activity, and fatty acid composition in the striatum of Parkinson's disease mouse model. J. Oleo Sci. 62(1) , 21-8, (2013) Active oxygen has been implicated in the pathogenesis of Parkinson's disease (PD); therefore, antioxidants have attracted attention as a potential way to prevent this disease. Squalene, a natural trit... | |
Synonyms
| Squalane |
| Robane |
| Cosbiol |
| Perhydrosqualene |
| 2,6,10,15,19,23-hexamethylteracosane |
| Spinacane |
| 2,6,10,15,19,23-Hexamethyltetracosane |
| Dodecahydrosqualene |
| 2,6,10,15,19,23-Hexamethyltetracosane,Cosbiol,Perhydrosqualene |
| Vitabiosol |
| MFCD00008953 |
| Hexamethyltetracosane |
| EINECS 203-825-6 |
| Tetracosane, 2,6,10,15,19,23-hexamethyl- |
| poly(ethylenepropylene) |
