Introduction：Basic information about CAS 2167-85-3|Pipazethate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Pipazethate |
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| CAS Number | 2167-85-3 | Molecular Weight | 399.50700 |
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| Density | 1.26g/cm3 | Boiling Point | 553.3ºC at 760mmHg |
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| Molecular Formula | C21H25N3O3S | Melting Point | / |
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| MSDS | / | Flash Point | 288.4ºC |
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Names
| Name | 2-(2-piperidin-1-ylethoxy)ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate |
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| Synonym | More Synonyms |
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Pipazethate BiologicalActivity
| Description | Pipazethate (SKF 70230A), a pyridobenzothiazine derivative, is a potent GABA antagonist. Pipazethate has antitussive activity. Pipazethate can be used in research in cough supressant[1]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Membrane Transporter/Ion Channel >>GABA ReceptorSignaling Pathways >>Neuronal Signaling >>GABA Receptor |
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Chemical & Physical Properties
| Density | 1.26g/cm3 |
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| Boiling Point | 553.3ºC at 760mmHg |
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| Molecular Formula | C21H25N3O3S |
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| Molecular Weight | 399.50700 |
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| Flash Point | 288.4ºC |
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| Exact Mass | 399.16200 |
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| PSA | 80.20000 |
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| LogP | 4.32630 |
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| Vapour Pressure | 2.76E-12mmHg at 25°C |
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| Index of Refraction | 1.612 |
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| InChIKey | DTVJXCOMJLLMAK-UHFFFAOYSA-N |
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| SMILES | O=C(OCCOCCN1CCCCC1)N1c2ccccc2Sc2cccnc21 |
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Toxicological Information
CHEMICAL IDENTIFICATION - RTECS NUMBER :
- UU8485000
- CHEMICAL NAME :
- 10H-Pyrido(3,2-b)(1,4)benzothiazine-10-carboxylic acid, 2-(2-(1-piperidinyl)ethoxy) ethyl ester
- CAS REGISTRY NUMBER :
- 2167-85-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H25-N3-O3-S
- MOLECULAR WEIGHT :
- 399.55
HEALTH HAZARD DATAACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 94647 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 188,189,1970
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 13140 ug/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 188,189,1970
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Synonyms
| 4-Aza-phenothiazin-10-carbonsaeure-piperidino-aethoxy-aethylester |
| Pipazetato [INN-Spanish] |
| Pipazetate |
| Pipazetatum [INN-Latin] |
| pipazethate |
| Theratuss |
| benzo[b]pyrido[2,3-e][1,4]thiazine-10-carboxylic acid 2-(2-piperidin-1-yl-ethoxy)-ethyl ester |
| Lenopect |
