CAS 84540-64-7|tris succinate
Introduction：Basic information about CAS 84540-64-7|tris succinate, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | tris succinate | ||
|---|---|---|---|
| CAS Number | 84540-64-7 | Molecular Weight | 360.35800 |
| Density | / | Boiling Point | 633.5ºC at 760 mmHg |
| Molecular Formula | C12H28N2O10 | Melting Point | 138-141ºC |
| MSDS | / | Flash Point | 336.9ºC |
Names
| Name | tris succinate |
|---|---|
| Synonym | More Synonyms |
tris succinate BiologicalActivity
| Description | Succinic acid tromethamine is a potent and orally active anxiolytic agent. Succinic acid tromethamine is an intermediate product of the tricarboxylic acid cycle. Succinic acid tromethamine can be used as a precursor of many industrially important chemicals in food, chemical and pharmaceutical industries[1][2][3]. |
|---|---|
| Related Catalog | Research Areas >>Neurological Disease |
| Target | Microbial Metabolite Human Endogenous Metabolite |
| In Vitro | Succinic acid tromethamine is derived from the fermentation of agricultural carbohydrates[2]. |
| In Vivo | Succinic acid tromethamine (3, 6 mg/kg; p.o.) increases the percentage of entries into open arms and of time spent on open arms in male mice[3]. Succinic acid tromethamine (3, 6, 12 mg/kg; i.p.) significant increases in food intake during 5 min, and 40 min after drug administration rectal temperature was measured, succinic acid at a dose of 1.5 mg/kg, inhibited stress-induced hyperthermia[3]. |
| References | [1]. Zhang YJ, et al. Optimization of succinic acid fermentation with Actinobacillus succinogenes by response surface methodology (RSM). J Zhejiang Univ Sci B. 2012 Feb;13(2):103-10. [2]. A T JOHNS, et al. The production of propionic acid by decarboxylation of succinic acid in a bacterial fermentation. Biochem J. 1948;42(1):ii. [3]. Si Wei Chen, Anxiolytic-like effect of succinic acid in mice. Life Sci. 2003 Nov 7;73(25):3257-64. |
Chemical & Physical Properties
| Boiling Point | 633.5ºC at 760 mmHg |
|---|---|
| Melting Point | 138-141ºC |
| Molecular Formula | C12H28N2O10 |
| Molecular Weight | 360.35800 |
| Flash Point | 336.9ºC |
| Exact Mass | 360.17400 |
| PSA | 248.02000 |
| InChIKey | CFJZQNZZGQDONE-UHFFFAOYSA-N |
| SMILES | NC(CO)(CO)CO.NC(CO)(CO)CO.O=C(O)CCC(=O)O |
Safety Information
| Safety Phrases | 24/25 |
|---|
Synonyms
| TRIS(HYDROXYMETHYL)AMINOMETHANE SUCCINATE |
| TRIS-SUCCINATE |
| succinic acid,compound with 2-amino-2-(hydroxymethyl)propane-1,3-diol (1:1) |
| TRIZMA SUCCINATE |
| DI[TRIS(HYDROXYMETHYL)AMINOMETHANE] SUCCINATE |
| 2-AMINO-2-(HYDROXYMETHYL)-1,3-PROPANEDIOL SUCCINATE |
