CAS 113-73-5|Gramicidin S
Introduction：Basic information about CAS 113-73-5|Gramicidin S, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Gramicidin S | ||
|---|---|---|---|
| CAS Number | 113-73-5 | Molecular Weight | 1141.447 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 1394.8±65.0 °C at 760 mmHg |
| Molecular Formula | C60H92N12O10 | Melting Point | / |
| MSDS | / | Flash Point | 797.4±34.3 °C |
Names
| Name | gramicidin S |
|---|---|
| Synonym | More Synonyms |
Gramicidin S BiologicalActivity
| Description | Gramicidin S (Gramicidin soviet) is a cationic cyclic peptide antibiotic. Gramicidin S is active against Gram-negative and Gram-positive bacteria by perturbing integrity of the bacterial membranes. Gramicidin S also inhibits cytochrome bd quinol oxidase[1]. |
|---|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
| References | [1]. Mogi T, et al. Gramicidin S and polymyxins: the revival of cationic cyclic peptide antibiotics. Cell Mol Life Sci. 2009 Dec;66(23):3821-6. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 1394.8±65.0 °C at 760 mmHg |
| Molecular Formula | C60H92N12O10 |
| Molecular Weight | 1141.447 |
| Flash Point | 797.4±34.3 °C |
| Exact Mass | 1140.705933 |
| PSA | 353.38000 |
| LogP | 0.10 |
| Vapour Pressure | 0.0±0.3 mmHg at 25°C |
| Index of Refraction | 1.596 |
| InChIKey | IUAYMJGZBVDSGL-XNNAEKOYSA-N |
| SMILES | CC(C)CC1NC(=O)C(CCCN)NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(Cc2ccccc2)NC(=O)C(CC(C)C)NC(=O)C(CCCN)NC(=O)C(C(C)C)NC(=O)C2CCCN2C(=O)C(Cc2ccccc2)NC1=O |
Synonyms
| 5H,22H-dipyrrolo[1,2-a:1',2'-p][1,4,7,10,13,16,19,22,25,28]decaazacyclotriacontine-5,22-dione, 12,29-bis(3-aminopropyl)-1,2,3,6,9,12,15,17a,18,19,20,23,26,29,32,34a-hexadecahydro-8,11,14,17,25,28,31,34-octahydroxy-15,32-bis(1-methylethyl)-9,26-bis(2-methylpropyl)-6,23-bis(phenylmethyl)-, (6R,7E,9S,10E,12S,13E,15S,16E,17aS,23R,24E,26S,27E,29S,30E,32S,33E,34aS)- |
| Gramicidin C |
| Cyclo(L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl-L-leucyl-D-phenylalanyl-L-prolyl-L-valyl-L-ornithyl) |
| Gramacidine S [INN-French] |
| Gramicin S 1 |
| Gramicidinum S [INN-Latin] |
| Gramicidina S [INN-Spanish] |
| gramicidin s |
| Gramicin S-A |
