Introduction：Basic information about CAS 122520-79-0|Tyrphostin AG 30, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Tyrphostin AG 30 |
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| CAS Number | 122520-79-0 | Molecular Weight | 205.16700 |
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| Density | 1.559g/cm3 | Boiling Point | 465.6ºC at 760mmHg |
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| Molecular Formula | C10H7NO4 | Melting Point | / |
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| MSDS | / | Flash Point | 235.4ºC |
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Names
| Name | (E)-2-cyano-3-(3,4-dihydroxyphenyl)prop-2-enoic acid |
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| Synonym | More Synonyms |
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Tyrphostin AG 30 BiologicalActivity
| Description | Tyrphostin AG30 (AG30) is a potent protein tyrosine kinases (PTK) inhibitor. Tyrphostin AG30 (AG30) selectively inhibits self renewal induction by c-ErbB, and is able to inhibit activation of STAT5 by c-ErbB in primary erythroblasts[1][2]. |
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| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
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| References | [1]. Volberg T, et al. The effect of tyrosine-specific protein phosphorylation on the assembly of adherens-type junctions. EMBO J. 1992 May;11(5):1733-42. [2]. Wessely O, et al. Distinct roles of the receptor tyrosine kinases c-ErbB and c-Kit in regulating the balance between erythroid cell proliferation and differentiation. Cell Growth Differ. 1997 May;8(5):481-93. |
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Chemical & Physical Properties
| Density | 1.559g/cm3 |
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| Boiling Point | 465.6ºC at 760mmHg |
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| Molecular Formula | C10H7NO4 |
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| Molecular Weight | 205.16700 |
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| Flash Point | 235.4ºC |
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| Exact Mass | 205.03800 |
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| PSA | 101.55000 |
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| LogP | 1.08938 |
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| Vapour Pressure | 1.8E-09mmHg at 25°C |
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| Index of Refraction | 1.717 |
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| InChIKey | CJMWBHLWSMKFSM-XVNBXDOJSA-N |
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| SMILES | N#CC(=Cc1ccc(O)c(O)c1)C(=O)O |
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Safety Information
Synonyms
| 3.4-Dioxy-benzylidencyanessigsaeure |
| 2-cyano-3-(3,4-dihydroxy-phenyl)-acrylic acid |
| (E)-2-cyano-3-(3,4-dihydroxyphenyl)acrylic acid |
| AG 30 |
| 2-Propenoic acid,2-cyano-3-(3,4-dihydroxyphenyl)-,(E) |
| Tyrphostin AG 30 |
| (E)-2-Cyano-3-(3,4-dihydroxyphenyl)-2-propenoic acid |
| Tyrophostin AG 30 |
| 2-Cyan-3-(3,4-dihydroxy-phenyl)-acrylsaeure |
