Introduction：Basic information about CAS 14017-71-1|(-)-Praeruptorin A, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | (-)-Praeruptorin A |
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| CAS Number | 14017-71-1 | Molecular Weight | 386.40 |
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| Density | 1.3±0.1 g/cm3 | Boiling Point | 486.8±45.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O7 | Melting Point | / |
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| MSDS | / | Flash Point | 211.5±28.8 °C |
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Names
| Name | (9R,10R)-10-acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (Z)-2-methylbut-2-enoate |
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| Synonym | More Synonyms |
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(-)-Praeruptorin A BiologicalActivity
| Description | (-)-Praeruptorin A is a nature product that could be isolated from the roots of Peucedanum praeruptorum Dunn. (-)-Praeruptorin A relaxes ileum and tracheal smooth muscles by activating NO/cGMP signaling pathway. (-)-Praeruptorin A has dramatically therapeutic effects on hypertension mainly through acting as a Ca2+-influx blocker[1]. |
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| Related Catalog | Signaling Pathways >>Membrane Transporter/Ion Channel >>Calcium ChannelResearch Areas >>Cardiovascular Disease |
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| References | [1]. Xu Z, et, al. (+/-)-Praeruptorin A enantiomers exert distinct relaxant effects on isolated rat aorta rings dependent on endothelium and nitric oxide synthesis. Chem Biol Interact. 2010 Jul 30;186(2):239-46. |
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Chemical & Physical Properties
| Density | 1.3±0.1 g/cm3 |
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| Boiling Point | 486.8±45.0 °C at 760 mmHg |
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| Molecular Formula | C21H22O7 |
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| Molecular Weight | 386.40 |
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| Flash Point | 211.5±28.8 °C |
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| Exact Mass | 386.136566 |
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| PSA | 92.04000 |
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| LogP | 4.18 |
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| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
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| Index of Refraction | 1.574 |
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| InChIKey | XGPBRZDOJDLKOT-BDWBDONCSA-N |
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| SMILES | CC=C(C)C(=O)OC1C(OC(C)=O)c2c(ccc3ccc(=O)oc23)OC1(C)C |
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Safety Information
Synonyms
| (9R,10R)-10-Acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2Z)-2-methyl-2-butenoate |
| 2-Butenoic acid, 2-methyl-, (9R,10R)-10-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-9-yl ester, (2Z)- |
| (9R,10R)-10-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2Z)-2-methylbut-2-enoate |
| (9R,10R)-10-Acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-9-yl (2Z)-2-methylbut-2-enoate |
| (-)-Praeruptorin A |
