CAS 141-84-4|Rhodanine
| Common Name | Rhodanine | ||
|---|---|---|---|
| CAS Number | 141-84-4 | Molecular Weight | 133.192 |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 218.2ºC at 760mmHg |
| Molecular Formula | C3H3NOS2 | Melting Point | 165-169 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 85.7ºC |
| Symbol | GHS05, GHS07 | Signal Word | Danger |
Names
| Name | 2-sulfanylidene-1,3-thiazolidin-4-one |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
|---|---|
| Boiling Point | 218.2ºC at 760mmHg |
| Melting Point | 165-169 °C(lit.) |
| Molecular Formula | C3H3NOS2 |
| Molecular Weight | 133.192 |
| Flash Point | 85.7ºC |
| Exact Mass | 132.965607 |
| PSA | 86.49000 |
| LogP | 0.06 |
| Vapour Pressure | 0.128mmHg at 25°C |
| Index of Refraction | 1.712 |
| InChIKey | KIWUVOGUEXMXSV-UHFFFAOYSA-N |
| SMILES | O=C1CSC(=S)N1 |
| Storage condition | -20°C |
| Water Solubility | SOLUBLE IN HOT WATER |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1093,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1093,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,1093,1986
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 225 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FRZKAP Farmatsevtichnii Zhurnal (Kiev). (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.3- 1930- Volume(issue)/page/year: 17(1),36,1962
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 12,447,1904
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 32 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#04798
Safety Information
| Symbol | GHS05, GHS07 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H302-H318 |
| Precautionary Statements | P280-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
| Hazard Codes | Xn:Harmful; |
| Risk Phrases | R22;R41 |
| Safety Phrases | S22-S26-S39 |
| RIDADR | 3288 |
| WGK Germany | 3 |
| RTECS | VI7700000 |
| Packaging Group | II |
| Hazard Class | 6.1(a) |
| HS Code | 29341000 |
Customs
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| Rhodanine |
| 4-oxo-2-thioxo thiazolidine |
| 2-Thioxo-4-thiazolidinone,Rhodanine,2-thioxo-4-Thiazolidinone |
| 4-Thiazolidinone,2-thioxo |
| Rhodaninic acid |
| 2-Thioxo-4-thiazolidinone |
| Rhodanic acid |
| 4-Thiazolidinone, 2-thioxo- |
| 2-Thioxo-1,3-thiazolidin-4-one |
| 2-Sulfanyl-1,3-thiazol-4(5H)-one |
| 4-Oxo-2-thioxothiazoline |
| EINECS 205-505-1 |
| Rhodanin |
| 4(5H)-thiazolone, 2-mercapto- |
| MFCD00005488 |
| 2-thioxothiazolidin-4-one |
