CAS 59669-26-0|thiodicarb

Introduction：Basic information about CAS 59669-26-0|thiodicarb, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. thiodicarb BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Articles17
7. Synonyms

Common Name	thiodicarb
CAS Number	59669-26-0	Molecular Weight	354.469
Density	1.3±0.1 g/cm3	Boiling Point	433.8±28.0 °C at 760 mmHg
Molecular Formula	C₁₀H₁₈N₄O₄S₃	Melting Point	168-172°C
MSDS	ChineseUSA	Flash Point	216.2±24.0 °C
Symbol	GHS06, GHS09	Signal Word	Danger

Names

Name	thiodicarb
Synonym	More Synonyms

thiodicarb BiologicalActivity

Description	Thiodicarb is a carbamate insecticide used to control flies in animal and poultry houses and dairies. Thiodicarb is metabolized into methomyl in animals and plants, and subsequently degraded into carbon dioxide and acetonitrile[1].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Others >>Others
In Vitro	Thiodicarb exhibit both oral and contact activity against major Lepidoptera, Coleoptera, Diptera, and Hemiptera pests, which affect cotton, soya beans, maize, vines, fruit, and vegetables[1].
References	[1]. Md Musfiqur Rahman, et al. Simultaneous Determination and Identity Confirmation of Thiodicarb and Its Degradation Product Methomyl in Animal-Derived Foodstuffs Using High-Performance Liquid Chromatography With Fluorescence Detection and Tandem Mass Spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Jan 1;1040:97-104.

Chemical & Physical Properties

Density	1.3±0.1 g/cm3
Boiling Point	433.8±28.0 °C at 760 mmHg
Melting Point	168-172°C
Molecular Formula	C₁₀H₁₈N₄O₄S₃
Molecular Weight	354.469
Flash Point	216.2±24.0 °C
Exact Mass	354.049011
PSA	159.70000
LogP	1.52
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.575
InChIKey	XDOTVMNBCQVZKG-OXAWKVHCSA-N
SMILES	CSC(C)=NOC(=O)N(C)SN(C)C(=O)ON=C(C)SC

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: KJ4301050

CHEMICAL NAME :: Ethanimidothioic acid, N,N'-(thiobis((methylimino)carbonyloxy))bis-, dimethyl ester

CAS REGISTRY NUMBER :: 59669-26-0

LAST UPDATED :: 199806

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C10-H18-N4-O4-S3

MOLECULAR WEIGHT :: 354.50

WISWESSER LINE NOTATION :: 1SY1&UNOVN1&SN1&VONUY1&S1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 66 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(254),29,1988

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 520 mg/m3/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C181,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >1600 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JEENAI Journal of Economic Entomology. (Entomological Soc. of America, 4603 Calvert Rd., College Park, MD 20740) V.1- 1908- Volume(issue)/page/year: 70(6),803,1977

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 800 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PEMNDP Pesticide Manual. (The British Crop Protection Council, 20 Bridport Rd., Thornton Heath CR4 7QG, UK) V.1- 1968- Volume(issue)/page/year: 9,817,1991

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 556 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(254),29,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 6310 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 42(254),29,1988

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Bird - domestic

DOSE/DURATION :: 2023 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: DEVEAA Defense des Vegetaux. (Federation Nationale des Groupements de Protection des Cultures, 149, rue de Bercy, 75595 Paris Cedex, 12, France) V.1- 1947- Volume(issue)/page/year: 38,119,1984 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989

Safety Information

Symbol	GHS06, GHS09
Signal Word	Danger
Hazard Statements	H301-H330-H400
Precautionary Statements	P260-P273-P284-P310
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T+: Very toxic;
Risk Phrases	R25
Safety Phrases	S28-S36/37-S45
RIDADR	2757
RTECS	KJ4301050
Packaging Group	III
Hazard Class	6.1(b)

Articles17

Nematicides enhance growth and yield of rotylenchulus reniformis resistant cotton genotypes.

J. Nematol. 46(4) , 365-75, (2015)

Rotylenchulus reniformis resistant LONREN-1×FM966 breeding lines developed at Auburn University have demonstrated that the nematode resistance is accompanied by severe stunting, limited growth, and lo...

Tobacco budworm P-glycoprotein: biochemical characterization and its involvement in pesticide resistance.

Biochim. Biophys. Acta 1291(2) , 155-62, (1996)

Since pesticides have been shown to interact with P-glycoprotein (P-gp), the purpose of this study was to examine the possible role of P-gp in pesticide resistance in the tobacco budworm (Heliothis vi...

Thiodicarb and methomyl tissue distribution in a fatal multiple compounds poisoning.

J. Forensic Sci. 53(2) , 499-502, (2008)

Thiodicarb is a nonsystemic carbamate insecticide whose acetylcholinesterase activity is related to its main methomyl degradation product. A 40-year-old woman was found dead in her car. Empty packages...

Synonyms

semevin

LARVIN

SKIPPER

CHIPCO

NIVRAL

dimethyl N,N’-[thiobis[(methylimino)carbonyloxy]]bis[ethanimidothioate]

(3EZ,12EZ)-3,7,9,13-tetramethyl-5,11-dioxa-2,8,14-trithia-4,7,9,12-tetraazapentadeca-3,12-diene-6,10-dione

lepicron

MFCD00145401

Thiodicarb

EINECS 261-848-7

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