CAS 85509-19-9|Flusilazole

Introduction：Basic information about CAS 85509-19-9|Flusilazole, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. Flusilazole BiologicalActivity
3. Chemical & Physical Properties
4. Toxicological Information
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
5. Safety Information
6. Customs
7. Articles14
8. Synonyms

Common Name	Flusilazole
CAS Number	85509-19-9	Molecular Weight	315.393
Density	1.2±0.1 g/cm3	Boiling Point	392.5±52.0 °C at 760 mmHg
Molecular Formula	C₁₆H₁₅F₂N₃Si	Melting Point	51-53ºC
MSDS	ChineseUSA	Flash Point	191.2±30.7 °C
Symbol	GHS07, GHS08, GHS09	Signal Word	Danger

Names

Name	flusilazole
Synonym	More Synonyms

Flusilazole BiologicalActivity

Description	Flusilazole (DPX-H6573), an organosilane fungicide, has broad-spectrum antifungal effect. Flusilazole exhibits curative and preventative activities and is recommended for use in agriculture and horticulture[1].
Related Catalog	Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Fungal
References	[1]. D Fabio Mercado, et al. Reaction Kinetics and Mechanisms of Organosilicon Fungicide Flusilazole With Sulfate and Hydroxyl Radicals. Chemosphere. 2018 Jan;190:327-336.

Chemical & Physical Properties

Density	1.2±0.1 g/cm3
Boiling Point	392.5±52.0 °C at 760 mmHg
Melting Point	51-53ºC
Molecular Formula	C₁₆H₁₅F₂N₃Si
Molecular Weight	315.393
Flash Point	191.2±30.7 °C
Exact Mass	315.100342
PSA	30.71000
LogP	3.84
Vapour Pressure	0.0±0.9 mmHg at 25°C
Index of Refraction	1.563
InChIKey	FQKUGOMFVDPBIZ-UHFFFAOYSA-N
SMILES	C[Si](Cn1cncn1)(c1ccc(F)cc1)c1ccc(F)cc1
Storage condition	0-6°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: XZ4105000

CHEMICAL NAME :: 1H-1,2,4-Triazole, 1-((bis(4-fluorophenyl)methylsilyl)methyl)-

CAS REGISTRY NUMBER :: 85509-19-9

LAST UPDATED :: 199710

DATA ITEMS CITED :: 5

MOLECULAR FORMULA :: C16-H15-F2-N3-Si

MOLECULAR WEIGHT :: 315.43

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 674 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PBCDDQ Proceedings-British Crop Protection Conference-Pests and Diseases. (British Crop., Protection Council, 2A Kidderminster Rd., Croydon, CRO 2UE, UK) 1977- Volume(issue)/page/year: -,413,1984

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PBCDDQ Proceedings-British Crop Protection Conference-Pests and Diseases. (British Crop., Protection Council, 2A Kidderminster Rd., Croydon, CRO 2UE, UK) 1977- Volume(issue)/page/year: -,413,1984

TYPE OF TEST :: LC50 - Lethal concentration, 50 percent kill

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Mammal - species unspecified

DOSE/DURATION :: >5 gm/m3

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: FMCHA2 Farm Chemicals Handbook. (Meister Pub., 37841 Euclid Ave., Willoughy, OH 44094) Volume(issue)/page/year: -,C142,1991

Safety Information

Symbol	GHS07, GHS08, GHS09
Signal Word	Danger
Hazard Statements	H302-H351-H360D-H411
Precautionary Statements	P201-P273-P281-P308 + P313
Personal Protective Equipment	Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
Hazard Codes	T:Toxic;N:Dangerousfortheenvironment;
Risk Phrases	R61;R22;R40;R51/53
Safety Phrases	S53-S45-S61
RIDADR	UN 2588
RTECS	XZ4105000
HS Code	2933990015

Customs

HS Code	2933990015
Summary	2933990015 3-((1h-1,2,4-triazol-1-yl)methyl)-1-(4-chlorophenyl)-4,4-dimethylpentan-3-ol。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:20.0%

Articles14

Real-time 2D separation by LC × differential ion mobility hyphenated to mass spectrometry.

Anal. Bioanal. Chem 402(8) , 2555-64, (2012)

The liquid chromatography-mass spectrometry (LC-MS) analysis of complex samples such as biological fluid extracts is widespread when searching for new biomarkers as in metabolomics. The success of thi...

Effects of two systemic fungicides: Artea (Propiconazole+cyproconazole) and Punch (Flusilazole) on the physiology and the respiratory metabolism of durum wheat (Triticum durum L.).

Commun. Agric. Appl. Biol. Sci. 71(3 Pt B) , 1041-8, (2006)

The present work aimed at the study of the effects of Artea and Punch; two systemic fungicides on durum Wheat (Triticum durum L. cv. GTA dur). Seeds were grown in a medium containing respectively 25, ...

Concentration-response analysis of differential gene expression in the zebrafish embryotoxicity test following flusilazole exposure.

Toxicol. Sci. 127(1) , 303-12, (2012)

The zebrafish embryotoxicity test (ZET) is considered a promising alternative model in predictive toxicology. Currently, morphological assessment of the embryo is the main readout for this assay. Howe...

Synonyms

bis(4-fluorophenyl)-methyl-(1,2,4-triazol-1-ylmethyl)silane

Caswell No. 419K

1-{[Bis(4-fluorophenyl)(methyl)silyl]methyl}-1H-1,2,4-triazole

T5NN DNJ A1-SI-1&R DF&R DF

Fluzilazol

1-[(Bis(4-fluorophenyl)methylsilyl)methyl]-1H-1,2,4-triazole

Sanction

Flusilazol

Punch

1-[[Bis(4-fluorophenyl)methylsilyl]methyl]-1H-1,2,4-triazole

Olymp

Flusilazole

UNII-F3WG2VVD87

MFCD01076615

dpx h6573

1H-1,2,4-Triazole, 1-[[bis(4-fluorophenyl)methylsilyl]methyl]-

Nustar

bis(4-fluorophenyl)(methyl)(1H-1,2,4-triazol-1-ylmethyl)silane

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