CAS 15545-48-9|Chlortoluron
Introduction：Basic information about CAS 15545-48-9|Chlortoluron, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Chlortoluron | ||
|---|---|---|---|
| CAS Number | 15545-48-9 | Molecular Weight | 212.676 |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 345.9±52.0 °C at 760 mmHg |
| Molecular Formula | C10H13ClN2O | Melting Point | 147-148ºC |
| MSDS | ChineseUSA | Flash Point | 163.0±30.7 °C |
| Symbol | GHS08, GHS09 | Signal Word | Warning |
Names
| Name | chlorotoluron |
|---|---|
| Synonym | More Synonyms |
Chlortoluron BiologicalActivity
| Description | Chlorotoluron (Chlortoluron) is a substituted phenylurea herbicide, is widely used for selective weed control in cereals crops and is an environmental pollutant[1]. |
|---|---|
| Related Catalog | Research Areas >>OthersSignaling Pathways >>Others >>Others |
| References | [1]. Z Mehmood, et al. Metabolism of the Herbicide Chlortoluron by Human Cytochrome P450 3A4. Chemosphere. 1995 Dec;31(11-12):4515-29. |
Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 345.9±52.0 °C at 760 mmHg |
| Melting Point | 147-148ºC |
| Molecular Formula | C10H13ClN2O |
| Molecular Weight | 212.676 |
| Flash Point | 163.0±30.7 °C |
| Exact Mass | 212.071640 |
| PSA | 32.34000 |
| LogP | 2.62 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.541 |
| InChIKey | JXCGFZXSOMJFOA-UHFFFAOYSA-N |
| SMILES | Cc1ccc(NC(=O)N(C)C)cc1Cl |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5800 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1300 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 21 gm/kg/90D-C
- TOXIC EFFECTS :
- Behavioral - food intake (animal) Nutritional and Gross Metabolic - weight loss or decreased weight gain Related to Chronic Data - death
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 2 gm/kg
- SEX/DURATION :
- female 4 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 10 mg/kg
- SEX/DURATION :
- male 50 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetotoxicity (except death, e.g., stunted fetus)
MUTATION DATA - TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,353,1978
- TEST SYSTEM :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 58,353,1978
Safety Information
| Symbol | GHS08, GHS09 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H351-H361d-H410 |
| Precautionary Statements | P273-P281-P501 |
| Hazard Codes | Xn:Harmful;N:Dangerousfortheenvironment; |
| Risk Phrases | R40;R50/53;R63 |
| Safety Phrases | S26-S36/37-S46-S60-S61-S16 |
| RIDADR | UN 3077 |
| RTECS | YS7230000 |
| HS Code | 2924299035 |
Customs
| HS Code | 2924299035 |
|---|---|
| Summary | 2924299035 2-chlorobenzaldehyde。supervision conditions:s(import or export registration certificate for pesticides)。VAT:17.0%。tax rebate rate:9.0%。MFN tarrif:6.5%。general tariff:30.0% |
Articles26
More Articles| Assessing the potential for algae and macrophytes to degrade crop protection products in aquatic ecosystems. Environ. Toxicol. Chem. 30(3) , 622-31, (2011) Rates of pesticide degradation in aquatic ecosystems often differ between those observed within laboratory studies and field trials. Under field conditions, a number of additional processes may well h... | |
| Polymer monolith microextraction using poly(butyl methacrylate-co-1,6-hexanediol ethoxylate diacrylate) monolithic sorbent for determination of phenylurea herbicides in water samples. Talanta 147 , 199-206, (2015) In this study, recently developed 1,6-hexanediol ethoxylate diacrylate (HEDA)-based polymeric monoliths were utilized as sorbents for efficient extraction of phenylurea herbicides (PUHs) from water sa... | |
| Analysis of trace levels of pesticides in rainwater by SPME and GC-tandem mass spectrometry after derivatisation with PFBBr. Anal. Bioanal. Chem 387(1) , 359-68, (2007) Solid-phase microextraction (SPME) was used for the analysis of some pesticides (bromoxynil, chlorotoluron, diuron, isoproturon, 2,4-MCPA, MCPP and 2,4-D) in rainwater after derivatisation with PFBBr ... |
Synonyms
| Chlorotoluron |
| Methanol, 1-[(3-chloro-4-methylphenyl)imino]-1-(dimethylamino)-, (E)- |
| Urea, N'-(3-chloro-4-methylphenyl)-N,N-dimethyl- |
| N’-(3-chloro-4-methylphenyl)-N,N-dimethylurea |
| 3-(3-Chloro-4-methylphenyl)-1,1-dimethylurea |
| MFCD00018275 |
| Chlortoluron |
| 3-(3-chloro-p-tolyl)-1,1-dimethylurea |
| EINECS 239-592-2 |
| 3-(3-Chloro-4-methyl)-1,1-dimethylurea |
| N'-(3-Chloro-4-methylphenyl)-N,N-dimethylcarbamimidic acid |
