CAS 91-22-5|leucoline
Introduction：Basic information about CAS 91-22-5|leucoline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | leucoline | ||
|---|---|---|---|
| CAS Number | 91-22-5 | Molecular Weight | 129.159 |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 234.1±9.0 °C at 760 mmHg |
| Molecular Formula | C9H7N | Melting Point | −17-−13 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 101.1±0.0 °C |
| Symbol | GHS06, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | quinoline |
|---|---|
| Synonym | More Synonyms |
Chemical & Physical Properties
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 234.1±9.0 °C at 760 mmHg |
| Melting Point | −17-−13 °C(lit.) |
| Molecular Formula | C9H7N |
| Molecular Weight | 129.159 |
| Flash Point | 101.1±0.0 °C |
| Exact Mass | 129.057846 |
| PSA | 12.89000 |
| LogP | 2.08 |
| Vapour density | 4.5 (vs air) |
| Vapour Pressure | 0.1±0.4 mmHg at 25°C |
| Index of Refraction | 1.642 |
| InChIKey | SMWDFEZZVXVKRB-UHFFFAOYSA-N |
| SMILES | c1ccc2ncccc2c1 |
| Stability | Stable. Incompatible with strong acids, strong oxidizing agents. May discolour on exposure to light. Hygroscopic - protect from moisture. Reacts violently and unpredictably with some materials, especially strong oxidizing agents. |
| Water Solubility | slightly soluble |
Toxicological Information
CHEMICAL IDENTIFICATION |
ACUTE TOXICITY DATA - TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 331 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 540 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7770 mg/kg/37W-C
- TOXIC EFFECTS :
- Tumorigenic - neoplastic by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 50 gm/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 9042 ug/kg/15D-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors Blood - lymphoma, including Hodgkin's disease
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 23 gm/kg/30W-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Liver - tumors
- TYPE OF TEST :
- Micronucleus test
- TYPE OF TEST :
- Mutation in mammalian somatic cells
MUTATION DATA - TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 110 ug/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7,1,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84566 No. of Facilities: 258 (estimated) No. of Industries: 7 No. of Occupations: 7 No. of Employees: 29238 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84566 No. of Facilities: 456 (estimated) No. of Industries: 9 No. of Occupations: 16 No. of Employees: 4241 (estimated) No. of Female Employees: 810 (estimated)
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Ovary
- DOSE/DURATION :
- 110 ug/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 7,1,1985 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 84566 No. of Facilities: 258 (estimated) No. of Industries: 7 No. of Occupations: 7 No. of Employees: 29238 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84566 No. of Facilities: 456 (estimated) No. of Industries: 9 No. of Occupations: 16 No. of Employees: 4241 (estimated) No. of Female Employees: 810 (estimated)
Safety Information
| Symbol | GHS06, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H312-H315-H319-H341-H350-H411 |
| Precautionary Statements | P201-P273-P280-P301 + P310-P305 + P351 + P338-P308 + P313 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R21/22;R37/38;R40;R41;R68 |
| Safety Phrases | S26-S36/37/39-S36-S23 |
| RIDADR | UN 2656 6.1/PG 3 |
| WGK Germany | 2 |
| RTECS | VA9275000 |
| Packaging Group | III |
| Hazard Class | 6.1 |
| HS Code | 2933499090 |
Customs
| HS Code | 2933499090 |
|---|---|
| Summary | 2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Synonyms
| 1-Azanaphthalene |
| Chinolin |
| EINECS 202-051-6 |
| 1-Benzazine |
| Quinolin |
| Chinoline |
| leucoline |
| Leucol |
| β-Quinoline |
| Quinoline |
| MFCD00006736 |
| Chinoleine |
| Benzopyridine |
| Fasudil Impurity 8 |
