CAS 123997-26-2|Eprinomectin
| Common Name | Eprinomectin | ||
|---|---|---|---|
| CAS Number | 123997-26-2 | Molecular Weight | 914.13 |
| Density | 1.23 | Boiling Point | / |
| Molecular Formula | C50H75NO14 | Melting Point | 163-166 ºC |
| MSDS | ChineseUSA | Flash Point | 2 °C |
| Symbol | GHS06, GHS08, GHS09 | Signal Word | Danger |
Names
| Name | eprinomectin |
|---|---|
| Synonym | More Synonyms |
Eprinomectin BiologicalActivity
| Description | Eprinomectin(MK-397) is an avermectin selected for development as a topical endectocide; has anthelmintic, insecticidal and miticidal activity. |
|---|---|
| Related Catalog | Signaling Pathways >>Anti-infection >>ParasiteResearch Areas >>Infection |
| References | [1]. Baoliang P, et al. Pharmacokinetics of eprinomectin in plasma and milk following subcutaneous administration to lactating dairy cattle. Vet Res Commun. 2006 Apr;30(3):263-70. [2]. Visser M, et al. The treatment of bovine sarcoptic mange (Sarcoptes scabiei var. bovis) using eprinomectin extended-release injection. Vet Parasitol. 2013 Mar 1;192(4):359-64. [3]. Shoop WL, et al. Eprinomectin: a novel avermectin for use as a topical endectocide for cattle. Int J Parasitol. 1996 Nov;26(11):1237-42. |
Chemical & Physical Properties
| Density | 1.23 |
|---|---|
| Melting Point | 163-166 ºC |
| Molecular Formula | C50H75NO14 |
| Molecular Weight | 914.13 |
| Flash Point | 2 °C |
| PSA | 178.93000 |
| LogP | 5.46970 |
| Storage condition | 2-8°C |
Safety Information
| Symbol | GHS06, GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H301-H361-H400 |
| Precautionary Statements | P273-P281-P301 + P310 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges |
| Hazard Codes | F,Xn,N,T |
| Risk Phrases | 11-20/21/22-36-62-50/53-25-63 |
| Safety Phrases | 26-36/37-16-61-60-45 |
| RIDADR | UN 2811 |
| WGK Germany | 3 |
Articles38
More Articles| Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel, against the ticks, Ixodes ricinus and Ixodes scapularis, on cats. Vet. Parasitol. 202(1-2) , 59-63, (2014) Five controlled, blinded and randomized studies were conducted to examine the efficacy of a single topical application of a combination of fipronil, (S)-methoprene, eprinomectin, and praziquantel (BRO... | |
| Efficacy of a single dose of a novel topical combination product containing eprinomectin to prevent heartworm infection in cats Vet. Parasitol. 202(1-2) , 49-53, (2014) Cats may be infected by heartworm, Dirofilaria immitis, through mosquito bites. They can develop severe heartworm disease when infective D. immitis larvae migrate and develop into adults in the pulmon... | |
| Efficacy of a novel topical combination of fipronil, (S)-methoprene, eprinomectin and praziquantel against experimental infections ofToxascaris leoninain cats Vet. Parasitol. 202(1-2) , 40-4, (2014) The efficacy of a novel topical fipronil, (S)-methoprene, eprinomectin and praziquantel combination product (BROADLINE®, Merial) was evaluated against adult Toxascaris leonina ascarids in experimental... |
Synonyms
| (4''R)-4''-(Acetylamino)-4''-deoxyavermectin B1 |
| (1'R,2S,4'S,5S,6R,8'R,10'E,12'S,13'S,14'E,16'E,20'R,21'R,24'S)-21',24'-Dihydroxy-6-isopropyl-5,11',13',22'-tetramethyl-2'-oxo-5,6-dihydrospiro[pyran-2,6'-[3,7,19]trioxatetracyclo[15.6.1.1.0]pentacosa[10,14,16,22]tetraen]-12'-yl 4-O-(4-acetamido-2,4,6-trideoxy-3-O-methyl-α-L-lyxo-hexopyranosyl)-2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranoside - (1'R,2S,4'S,5S,6R,8'R,10'E,12'S,1 3'S,14'E,16'E,20'R,21'R,24'S)-6-[(2S)-2-buta |
| Eprinomectin |
| Eprinex |
| EINECS 200-835-2 |
| MFCD07370747 |
