CAS 86-74-8|Carbazole
| Common Name | Carbazole | ||
|---|---|---|---|
| CAS Number | 86-74-8 | Molecular Weight | 167.207 |
| Density | 1.1 | Boiling Point | 355.0±11.0 °C at 760 mmHg |
| Molecular Formula | C12H9N | Melting Point | 243-246 °C(lit.) |
| MSDS | ChineseUSA | Flash Point | 220 ºC |
| Symbol | GHS08 | Signal Word | Warning |
Names
| Name | 9H-carbazole |
|---|---|
| Synonym | More Synonyms |
Carbazole BiologicalActivity
| Description | Carbazole is a tricyclic aromatic heterocyclic. Carbazole can form a new type of DNA minor groove complex to suppress the synthesis of new DNA or RNA[1]. |
|---|---|
| Related Catalog | Signaling Pathways >>Cell Cycle/DNA Damage >>DNA/RNA SynthesisResearch Areas >>Others |
| References | [1]. F A Tanious, et al. A new type of DNA minor-groove complex: carbazole dication-DNA interactions. Biochemistry. 1997 Dec 9;36(49):15315-25. [2]. carbazole and its derivatives as antitumor agents. Anticancer Agents Med Chem. 2015;15(8):1049-65. [3]. Kai Lin Woon, et al. Effect of conjugation and aromaticity of 3,6 di-substituted carbazoles on triplet energy and the implication of triplet energy in multiple-cyclic aromatic compounds. RSC Adv., 2018, 8, 9850-9857. |
Chemical & Physical Properties
| Density | 1.1 |
|---|---|
| Boiling Point | 355.0±11.0 °C at 760 mmHg |
| Melting Point | 243-246 °C(lit.) |
| Molecular Formula | C12H9N |
| Molecular Weight | 167.207 |
| Flash Point | 220 ºC |
| Exact Mass | 167.073502 |
| PSA | 15.79000 |
| LogP | 3.72 |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Index of Refraction | 1.768 |
| InChIKey | UJOBWOGCFQCDNV-UHFFFAOYSA-N |
| SMILES | c1ccc2c(c1)[nH]c1ccccc12 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents, nitrogen oxides, potassium hydroxide. |
| Water Solubility | <0.1 g/100 mL at 19 ºC |
Safety Information
| Symbol | GHS08 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H351-H413 |
| Precautionary Statements | P281 |
| Target Organs | Blood, Central nervous system, Liver |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | Xn:Harmful |
| Risk Phrases | R40;R50/53 |
| Safety Phrases | S26-S36-S60-S61-S36/37-S24/25-S23-S53 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 2 |
| RTECS | FE3150000 |
| Packaging Group | III |
| Hazard Class | 9 |
| HS Code | 2933990090 |
Customs
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Articles53
More Articles| Convenient QSAR model for predicting the complexation of structurally diverse compounds with β-cyclodextrins Bioorg. Med. Chem. 17 , 896-904, (2009) This paper reports a QSAR study for predicting the complexation of a large and heterogeneous variety of substances (233 organic compounds) with beta-cyclodextrins (beta-CDs). Several different theoret... | |
| Electromechanical response of silk fibroin hydrogel and conductive polycarbazole/silk fibroin hydrogel composites as actuator material. Mater. Sci. Eng. C. Mater. Biol. Appl. 56 , 1-8, (2015) Pure silk fibroin (SF) hydrogel and polycarbazole/silk fibroin (SF/PCZ) hydrogels were fabricated by solvent casting technique to evaluate electromechanical responses, dielectric properties, and canti... | |
| Clausenawallines G-K, carbazole alkaloids from Clausena wallichii twigs. Phytochemistry 88 , 74-8, (2013) Five carbazole alkaloids, clausenawallines G-K (1-5), along with 12 known alkaloids (6-17) were isolated from the twigs of Clausena wallichii. Their structures were established using spectroscopic met... |
Synonyms
| diphenylenimine |
| DIPHENYLIMIDE |
| Carbazole |
| polycarbazole |
| 2-(2-Bromoanilino)pyridine |
| Diphenylimid |
| 9H-CARBAZOLE |
| Dibenzopyrrol |
| EINECS 201-696-0 |
| 'LGC' (2409) |
| usafek-600 |
| dibenzopyrrole |
| 9-AZAFLUORENE |
| MFCD00004960 |
