Introduction：Basic information about CAS 20829-55-4|Cyclo(-Trp-Trp), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Cyclo(-Trp-Trp) |
|---|
| CAS Number | 20829-55-4 | Molecular Weight | 372.420 |
|---|
| Density | 1.4±0.1 g/cm3 | Boiling Point | 813.4±60.0 °C at 760 mmHg |
|---|
| Molecular Formula | C22H20N4O2 | Melting Point | / |
|---|
| MSDS | / | Flash Point | 445.7±32.9 °C |
|---|
Names
| Name | (3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione |
|---|
| Synonym | More Synonyms |
|---|
Cyclo(-Trp-Trp) BiologicalActivity
| Description | Cyclo(L-Trp-L-Trp) is an antibiotic, and shows antimicrobial activity. Cyclo(L-Trp-L-Trp) can inhibit A. baumannii, as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus. Cyclo(L-Trp-L-Trp) can be used in microbial infection research[1]. |
|---|
| Related Catalog | Research Areas >>InfectionSignaling Pathways >>Anti-infection >>Bacterial |
|---|
| In Vitro | Cyclo(L-Trp-L-Trp) can inhibit A. baumannii (MICs=12.5-25 µg/mL), as well as Candida albicans, Bacillus subtilis, Micrococcus luteus, Saccharomyces cerevisiae, Aspergillus niger, Staphylococcus aureus (MICs=12.5-50 µg/mL)[1]. |
|---|
| References | [1]. Keyong Ho Lee, et al. Identification of Streptomyces sp. KH29, which produces an antibiotic substance processing an inhibitory activity against multidrug-resistant Acinetobacter baumannii. J Microbiol Biotechnol. 2010 Dec;20(12):1672-6. |
|---|
Chemical & Physical Properties
| Density | 1.4±0.1 g/cm3 |
|---|
| Boiling Point | 813.4±60.0 °C at 760 mmHg |
|---|
| Molecular Formula | C22H20N4O2 |
|---|
| Molecular Weight | 372.420 |
|---|
| Flash Point | 445.7±32.9 °C |
|---|
| Exact Mass | 372.158630 |
|---|
| PSA | 89.78000 |
|---|
| LogP | 1.66 |
|---|
| Vapour Pressure | 0.0±2.9 mmHg at 25°C |
|---|
| Index of Refraction | 1.724 |
|---|
| InChIKey | DNHODRZUCGXYKU-PMACEKPBSA-N |
|---|
| SMILES | O=C1NC(Cc2c[nH]c3ccccc23)C(=O)NC1Cc1c[nH]c2ccccc12 |
|---|
Safety Information
Customs
| HS Code | 2933990090 |
|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
|---|
Synonyms
| cyclo-(L-Trp-L-Trp) |
| cyclo(L-tryptophanyl-L-tryptophanyl) |
| cyclo(tryptophyl-tryptophyl) |
| Cyclo(L-Trp-L-Trp) |
| Fellutanine A |
| (3S,6S)-3,6-bis(1H-indol-3-ylmethyl)piperazine-2,5-dione |
| (3S,6S)-3,6-Bis(1H-indol-3-ylmethyl)-2,5-piperazinedione |
| c-(L-Trp-L-Trp) |
| 3,6-Bis(1H-indol-3-ylmethyl)-2,5-piperazinedione |
| cyclo-L-tryptophan-L-tryptophan |
| 2,5-Piperazinedione, 3,6-bis(1H-indol-3-ylmethyl)- |
| cyclo(Trp-Trp) |
| 2,5-Piperazinedione, 3,6-bis(1H-indol-3-ylmethyl)-, (3S,6S)- |
