CAS 99287-07-7|Defensin HNP-2 human

Introduction:Basic information about CAS 99287-07-7|Defensin HNP-2 human, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common NameDefensin HNP-2 human
CAS Number99287-07-7Molecular Weight3370.95000
Density/Boiling Point/
Molecular FormulaC147H217N43O37S6Melting Point/
MSDSChineseUSAFlash Point/

Names

NameNeutrophil Peptide-2
SynonymMore Synonyms

Defensin HNP-2 human BiologicalActivity

DescriptionDefensin HNP-2 human is an endogenous antibiotic peptide and monocyte chemotactic peptide produced by human neutrophils.
Target

Human Endogenous Metabolite

Chemical & Physical Properties

Molecular FormulaC147H217N43O37S6
Molecular Weight3370.95000
Exact Mass3368.47000
PSA1445.83000
LogP6.15780
InChIKeyGRZXCHIIZXMEPJ-HTLKCAKFSA-N
SMILESCCC(C)C1NC(=O)C2CSSCC3NC(=O)C(Cc4ccccc4)NC(=O)C(C)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C(CC(C)C)NC(=O)C(CCCNC(=N)N)NC(=O)CNC(=O)C(CCC(N)=O)NC(=O)C(Cc4ccc(O)cc4)NC(=O)C(C(C)CC)NC(=O)C(CSSCC(NC(=O)C(Cc4ccc(O)cc4)NC(=O)C(N)CSSCC(C(=O)O)NC3=O)C(=O)NC(CCCNC(=N)N)C(=O)NC(C(C)CC)C(=O)N3CCCC3C(=O)NC(C)C(=O)N2)NC(=O)C(C(C)O)NC(=O)CNC(=O)C(Cc2ccc(O)cc2)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCC(=O)O)NC(=O)CNC(=O)C(C)NC1=O

Safety Information

Personal Protective EquipmentEyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADRNONH for all modes of transport
WGK Germany3

Articles4

More Articles
Structure, function, and membrane integration of defensins.

Curr. Opin. Struct. Biol. 5 , 521-527, (1995)

Defensins comprise a structural class of small cationic peptides that exert broad-spectrum antimicrobial activities through membrane permeabilization. Their predominantly beta-sheet structure, stabili...

Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin.

Infect. Immun. 55 , 2281, (1987)

A broad-spectrum antimicrobial peptide present in guinea pig neutrophils was isolated, characterized biochemically, and assessed for microbicidal range and potency in vitro. The guinea pig neutrophil ...

Human β-defensin-2. Schroder J.M., and Harder, J.

Int. J. Biochem. Cell Biol. 31 , 645-651, (1998)

Synonyms

Human neutrophil peptide 2 (CYCRIPACIAGERRYGTCIYQGRLWAFCC)
Defensin HNP-2 human
HNP2
HNP-2, Defensin Human Neutrophil Peptide-2
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