CAS 114681-65-1|H-Gly-Arg-Gly-Asp-Asn-Pro-OH

Introduction：Basic information about CAS 114681-65-1|H-Gly-Arg-Gly-Asp-Asn-Pro-OH, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.

Table of Contents

1. Names
2. H-Gly-Arg-Gly-Asp-Asn-Pro-OH BiologicalActivity
3. Chemical & Physical Properties
4. Synonyms

Common Name	H-Gly-Arg-Gly-Asp-Asn-Pro-OH
CAS Number	114681-65-1	Molecular Weight	614.61
Density	1.7±0.1 g/cm3	Boiling Point	/
Molecular Formula	C₂₃H₃₈N₁₀O₁₀	Melting Point	/
MSDS	/	Flash Point	/

Names

Name	H-Gly-Arg-Gly-Asp-Asn-Pro-OH
Synonym	More Synonyms

H-Gly-Arg-Gly-Asp-Asn-Pro-OH BiologicalActivity

Description	RGD peptide acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].
Related Catalog	Research Areas >>Inflammation/ImmunologySignaling Pathways >>Cytoskeleton >>Integrin
References	[1]. Ruoslahti, E., and Öbrink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996). [2]. Meredith JE Jr, et al. Integrins, adhesion and apoptosis. Trends Cell Biol. 1997 Apr;7(4):146-50. [3]. Yang W, et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. J Biol Chem. 1999 Mar 26;274(13):8524-30.

Description

RGD peptide acts as an inhibitor of integrin-ligand interactions and plays an important role in cell adhesion, migration, growth, and differentiation[1]. RGD peptides promote apoptosis through activation of conformation changes that enhance pro-caspase-3 activation and autoprocessing[2][3].

Related Catalog

Research Areas >>Inflammation/ImmunologySignaling Pathways >>Cytoskeleton >>Integrin

References

[1]. Ruoslahti, E., and Öbrink, B. Common principles in cell adhesion Experimental Cell Research 227, 1-11 (1996).

[2]. Meredith JE Jr, et al. Integrins, adhesion and apoptosis. Trends Cell Biol. 1997 Apr;7(4):146-50.

[3]. Yang W, et al. Activation of the Cdc42-associated tyrosine kinase-2 (ACK-2) by cell adhesion via integrin beta1. J Biol Chem. 1999 Mar 26;274(13):8524-30.

Chemical & Physical Properties

Density	1.7±0.1 g/cm3
Molecular Formula	C₂₃H₃₈N₁₀O₁₀
Molecular Weight	614.61
Exact Mass	614.277222
PSA	342.32000
LogP	-3.41
Index of Refraction	1.696
InChIKey	CWAHAVYVGPRZJU-XUXIUFHCSA-N
SMILES	NCC(=O)NC(CCCN=C(N)N)C(=O)NCC(=O)NC(CC(=O)O)C(=O)NC(CC(N)=O)C(=O)N1CCCC1C(=O)O
Storage condition	-15°C

Synonyms

REF DUPL: Gly-Arg-Gly-Asp-Asn-Pro

Glycyl-N-(diaminomethylene)-L-ornithylglycyl-L-α-aspartyl-L-asparaginyl-L-proline

RGD PEPTIDE

GRGDNP

L-Proline, glycyl-N-(diaminomethylene)-L-ornithylglycyl-L-α-aspartyl-L-asparaginyl-

Gly-Arg-Gly-Asp-Asn-Ser

GLY-ARG-GLY-ASP-ASN-PRO

RGD PEPTIDE (GRGDNP)

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