CAS 15588-23-5|(2H3)Hydroxylamine (2H)hydrochloride (1:1)

Introduction:Basic information about CAS 15588-23-5|(2H3)Hydroxylamine (2H)hydrochloride (1:1), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name(2H3)Hydroxylamine (2H)hydrochloride (1:1)
CAS Number15588-23-5Molecular Weight73.516
Density/Boiling Point/
Molecular FormulaClD4NOMelting Point156-158ºC(lit.)
MSDSChineseUSAFlash Point/
Symbol
GHS05, GHS07, GHS08, GHS09
Signal WordWarning

Names

NameHydroxylamine-d3 deuteriochloride
SynonymMore Synonyms

BiologicalActivity

DescriptionHydroxylamine-d3 (hydrochloride) is the deuterium labeled Hydroxyamine hydrochloride[1]. Hydroxyamine hydrochloride is a selective monoamine oxidase (MAO) inhibitor used for inhibiting of platelet aggregation. Hydroxyamine hydrochloride is an intermediate of organic synthesis[2].
Related CatalogResearch Areas >>Cardiovascular DiseaseSignaling Pathways >>Neuronal Signaling >>Monoamine Oxidase
In VitroStable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

[2]. Roh JH, et al. Purification, characterization, and crystallization of monoamine oxidase from Escherichia coli K-12. Biosci Biotechnol Biochem. 1994 Sep;58(9):1652-6.  

Chemical & Physical Properties

Melting Point156-158ºC(lit.)
Molecular FormulaClD4NO
Molecular Weight73.516
Exact Mass73.023247
PSA46.25000
LogP0.83660
InChIKeyWTDHULULXKLSOZ-MUONFQNCSA-N
SMILESCl.NO

Safety Information

Symbol
GHS05, GHS07, GHS08, GHS09
Signal WordWarning
Hazard StatementsH290-H302-H312-H315-H317-H319-H351-H373-H400
Precautionary StatementsP273-P280-P305 + P351 + P338
Hazard CodesT: Toxic;
Risk PhrasesR5
Safety Phrases22-24-26-37-45-61
RIDADRUN 2923 8/PG 2

Synonyms

(H)Hydroxylamine (H)hydrochloride (1:1)
hydroxylamine hydrochloride-d4
Hydroxylamine-d, hydrochloride-d (1:1)
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