Introduction:Basic information about CAS 808-26-4|Sancycline, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Sancycline |
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| CAS Number | 808-26-4 | Molecular Weight | 414.409 |
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| Density | 1.6±0.1 g/cm3 | Boiling Point | 750.9±60.0 °C at 760 mmHg |
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| Molecular Formula | C21H22N2O7 | Melting Point | 224-228ºC (dec) |
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| MSDS | / | Flash Point | 407.9±32.9 °C |
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Names
| Name | Sancycline |
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| Synonym | More Synonyms |
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Sancycline BiologicalActivity
| Description | Sancycline is a rare semi-synthetic tetracycline prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin。Target:Like other tetracyclines, sancycline acts by reversibly binding to the 30S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome A site. |
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| Related Catalog | Signaling Pathways >>Anti-infection >>BacterialResearch Areas >>Infection |
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Chemical & Physical Properties
| Density | 1.6±0.1 g/cm3 |
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| Boiling Point | 750.9±60.0 °C at 760 mmHg |
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| Melting Point | 224-228ºC (dec) |
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| Molecular Formula | C21H22N2O7 |
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| Molecular Weight | 414.409 |
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| Flash Point | 407.9±32.9 °C |
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| Exact Mass | 414.142700 |
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| PSA | 161.39000 |
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| LogP | -0.67 |
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| Vapour Pressure | 0.0±2.6 mmHg at 25°C |
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| Index of Refraction | 1.735 |
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| InChIKey | MTCQOMXDZUULRV-ADOAZJKMSA-N |
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| SMILES | CN(C)C1C(=O)C(C(N)=O)=C(O)C2(O)C(=O)C3=C(O)c4c(O)cccc4CC3CC12 |
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| Storage condition | 2-8℃ |
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Synonyms
| 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxo-, (4S,4aS,5aR,12aS)- |
| GS 2147 |
| 6-Demethyl-6-deoxytetracycline |
| 6-demethyl-6-deoxy-tetracycline |
| 6-deoxi-6-demethyl-tetracycline |
| Bonomycin |
| Sancycline |
| (4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-2-tetracenecarboxamide |
| Norcycline |
| (4S,4aS,5aR,12aS)-4-(Dimethylamino)-3,10,12,12a-tetrahydroxy-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide |