Introduction：Basic information about CAS 2623-33-8|Acetaminophen Acetate (Acetaminophen Impurity), including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
| Common Name | Acetaminophen Acetate (Acetaminophen Impurity) |
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| CAS Number | 2623-33-8 | Molecular Weight | 193.199 |
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| Density | 1.2±0.1 g/cm3 | Boiling Point | 376.4±25.0 °C at 760 mmHg |
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| Molecular Formula | C10H11NO3 | Melting Point | 155°C |
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| MSDS | ChineseUSA | Flash Point | 181.4±23.2 °C |
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Names
| Name | (4-acetamidophenyl) acetate |
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| Synonym | More Synonyms |
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BiologicalActivity
| Description | 4-Acetamidophenyl acetate is an impurity of Acetaminophen (paracetamol). Acetaminophen, an analgesic drug, is a selective COX-2 inhibitor (IC50=25.8 μM), and is a potent hepatic N-acetyltransferase 2 (NAT2) inhibitor[1][2]. |
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| Related Catalog | Signaling Pathways >>Others >>OthersResearch Areas >>Inflammation/Immunology |
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| References | [1]. Hinz, B, et al. Acetaminophen (paracetamol) is a selective cyclooxygenase-2 inhibitor in man. FASEB J, 2008. 22(2): p. 383-90. [2]. Rothen JP, et al. Acetaminophen is an inhibitor of hepatic N-acetyltransferase 2 in vitro and in vivo. Pharmacogenetics. 1998 Dec;8(6):553-9. |
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Chemical & Physical Properties
| Density | 1.2±0.1 g/cm3 |
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| Boiling Point | 376.4±25.0 °C at 760 mmHg |
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| Melting Point | 155°C |
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| Molecular Formula | C10H11NO3 |
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| Molecular Weight | 193.199 |
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| Flash Point | 181.4±23.2 °C |
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| Exact Mass | 193.073898 |
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| PSA | 55.40000 |
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| LogP | 0.60 |
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| Vapour Pressure | 0.0±0.9 mmHg at 25°C |
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| Index of Refraction | 1.561 |
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| Storage condition | Refrigerator |
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Safety Information
| Hazard Codes | Xi |
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| Risk Phrases | 36/37/38 |
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| Safety Phrases | S26-S36/37/39 |
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| RIDADR | NONH for all modes of transport |
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| HS Code | 2924299090 |
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Customs
| HS Code | 2924299090 |
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| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
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Articles2
More Articles
| Analysis of tablets containing aspirin, acetaminophen, and ascorbic acid by high-performance liquid chromatography. J. Pharm. Sci. 73(12) , 1830-3, (1984) The high-performance liquid chromatographic method described enables the quantitation of the components and the main impurities of tablets containing aspirin, acetaminophen, and ascorbic acid. A C8 re... | |
| [N,O-diacetyl-p-aminophenol formation by combined use of aspirin with phenacetin and acetaminophen in vivo (author's transl)]. Yakugaku Zasshi 100(10) , 1043-7, (1980)
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Synonyms
| 4-Acetamidophenyl acetate |
| Acetaminophen Acetate (Acetaminophen Impurity) |
| Acetaminophen acetate |
| EINECS 220-077-6 |
| 4-AcNHC6H4OAc |
| 4'-Acetoxyacetanilide |
| Diacetamat |
| P-ACETOXYACETANILIDE |
| Acetaminophen Related Compound A |
| MFCD00059205 |
| N,O-Diacetyl-4-aminophenol |
| 4-(Acetylamino)phenyl acetate,p-Acetoxyacetanilide |
| 4-Acetoxyacetanilide |
| Acetamide, N-[4-(acetyloxy)phenyl]- |
| diacetamate |
