CAS 5342-95-0|1-(Piperidinomethyl)-2-naphthol

CHEMICAL IDENTIFICATION

RTECS NUMBER :

QL4905000

CHEMICAL NAME :

2-Naphthol, 1-(piperidinomethyl)-

CAS REGISTRY NUMBER :

5342-95-0

BEILSTEIN REFERENCE NO. :

0185859

LAST UPDATED :

199612

DATA ITEMS CITED :

2

MOLECULAR FORMULA :

C16-H19-N-O

MOLECULAR WEIGHT :

241.36

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intravenous

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

46 mg/kg

TOXIC EFFECTS :

Behavioral - convulsions or effect on seizure threshold Lungs, Thorax, or Respiration - respiratory depression Gastrointestinal - changes in structure or function of salivary glands

REFERENCE :

BJPCAL British Journal of Pharmacology and Chemotherapy. (London, UK) V.1-33, 1946-68. For publisher information, see BJPCBM. Volume(issue)/page/year: 12,194,1957

TYPE OF TEST :

LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :

Subcutaneous

SPECIES OBSERVED :

Rodent - guinea pig

DOSE/DURATION :

200 mg/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 73,27,1941