CAS 1198-40-9|7-Chloro-4-quinolinamine

Introduction:Basic information about CAS 1198-40-9|7-Chloro-4-quinolinamine, including its chemical name, molecular formula, synonyms, physicochemical properties, and safety information, etc.
Common Name7-Chloro-4-quinolinamine
CAS Number1198-40-9Molecular Weight178.618
Density1.4±0.1 g/cm3Boiling Point366.8±27.0 °C at 760 mmHg
Molecular FormulaC9H7ClN2Melting Point96-97°C
MSDSChineseUSAFlash Point175.7±23.7 °C
Symbol
GHS06
Signal WordDanger

Names

Name7-Chloroquinolin-4-amine
SynonymMore Synonyms

Chemical & Physical Properties

Density1.4±0.1 g/cm3
Boiling Point366.8±27.0 °C at 760 mmHg
Melting Point96-97°C
Molecular FormulaC9H7ClN2
Molecular Weight178.618
Flash Point175.7±23.7 °C
Exact Mass178.029770
PSA38.91000
LogP2.38
Vapour Pressure0.0±0.8 mmHg at 25°C
Index of Refraction1.712
InChIKeyNDRZSRWMMUGOBP-UHFFFAOYSA-N
SMILESNc1ccnc2cc(Cl)ccc12
Water SolubilityREACTS

Safety Information

Symbol
GHS06
Signal WordDanger
Hazard StatementsH301-H319
Precautionary StatementsP301 + P310-P305 + P351 + P338
Hazard CodesC
Risk PhrasesR34:Causes burns. R40:Limited evidence of a carcinogenic effect. R14:Reacts violently with water.
Safety PhrasesS23-S24/25-S26-S36/37/39-S45-S22
RIDADRUN 3265 8/PG 2
WGK Germany2
RTECSRR4584700
Packaging GroupII
Hazard Class4.1
HS Code29420000

Customs

HS Code2933499090
Summary2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles8

More Articles
Overcoming drug resistance to heme-targeted antimalarials by systematic side chain variation of 7-chloro-4-aminoquinolines.

J. Med. Chem. 51(7) , 1995-8, (2008)

Systematic variation of the branching and basicity of the side chain of chloroquine yielded a series of new 7-chloro-4-aminoquinoline derivatives exhibiting high in vitro activity against four differe...

New chimeric antimalarials with 4-aminoquinoline moiety linked to a tetraoxane skeleton.

J. Med. Chem. 51(19) , 6216-9, (2008)

The synthesis of the chimeric molecules consisting of two pharmacophores, tetraoxane and 7-chloro-4-aminoquinoline, is reported. The tetraoxanes 2, 4, and 8 show relatively potent in vitro antimalaria...

An ELISA test for detecting chloroquine in urine.

Trans. R. Soc. Trop. Med. Hyg. 82(2) , 216-20, (1988)

Two ELISA tests for detecting chloroquine in urine have been developed using polyclonal and monoclonal antibodies which react with the 7-chloro-4-amino-quinoline part of the chloroquine molecule and t...

Synonyms

7-chloroquinolin-4-amine
4-Amino-7-chloroquinoline
4-Quinolinamine, 7-chloro-
7-Chloro-4-quinolinamine
7-chloro-quinolin-4-ylamine
7-chloro-4-aminoquinoline
MFCD00828822
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